Kaufmann R, Hartmann A, Hibst R
Department of Dermatology, University of Ulm, Germany.
J Dermatol Surg Oncol. 1994 Feb;20(2):112-8. doi: 10.1111/j.1524-4725.1994.tb00123.x.
Pulsed mid-infrared lasers allow a precise removal of soft tissues with only minimal thermal damage.
To study the potential dermatosurgical usefulness of currently available systems at different wavelengths (2010-nm Thulium:YAG laser, 2100-nm Holmium:YAG laser, 2790-nm Erbium:YSGG laser, and 2940-nm Erbium:YAG laser) in vivo on pig skin.
Immediate effects and wound healing of superficial laser-abrasions and incisions were compared with those of identical control lesions produced by dermabrasion, scalpel incisions, or laser surgery performed by a 1060-nm Nd:YAG and a 1060-nm CO2 laser (continuous and superpulsed mode).
Best efficiency and least thermal injury was found for the pulsed Erbium:YAG laser, leading to ablative and incisional lesions comparable to those obtained by dermabrasion or superficial scalpel incisions, respectively.
In contrast to other mid-infrared lasers tested, the 2940-nm Erbium:YAG laser thus provides a potential instrument for future applications in skin surgery, especially when aiming at a careful ablative removal of delicate superficial lesions with maximum sparing of adjacent tissue structures. However, in the purely incisional application mode pulsed mid-infrared lasers, though of potential usefulness in microsurgical indications (eg, surgery of the cornea), do not offer a suggestive alternative to simple scalpel surgery of the skin.
脉冲式中红外激光能够精确去除软组织,且热损伤极小。
研究目前可用的不同波长系统(2010纳米铥钇铝石榴石激光、2100纳米钬钇铝石榴石激光、2790纳米铒钇钪镓石榴石激光和2940纳米铒钇铝石榴石激光)在猪皮肤活体上的潜在皮肤外科应用价值。
将浅表激光磨皮和切口的即时效果及伤口愈合情况与通过磨皮、手术刀切口或1060纳米掺钕钇铝石榴石激光和1060纳米二氧化碳激光(连续和超脉冲模式)进行的激光手术产生的相同对照损伤的效果进行比较。
发现脉冲式铒钇铝石榴石激光效率最高且热损伤最小,分别产生与磨皮或浅表手术刀切口相当的磨蚀性和切口性损伤。
与其他测试的中红外激光不同,2940纳米铒钇铝石榴石激光因此为未来皮肤外科应用提供了一种潜在工具,特别是当旨在小心地消融去除精细的浅表病变并最大程度保留相邻组织结构时。然而,在纯切口应用模式下,脉冲式中红外激光虽然在显微外科适应症(如角膜手术)中可能有用,但对于简单的皮肤手术刀手术而言并非有吸引力的替代方法。