Liu Zhenzhen, Zhao Ronghua, Zou Zhongmei
Institute of Medicinal Plant Development, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100193, China.
Zhongguo Zhong Yao Za Zhi. 2011 Sep;36(18):2503-6.
To investigate chemical constituents of the root bark of Tripterygium hypoglaucum.
Compounds were isolated by column chromatography on silica gel and Sephadex LH-20, and their structures were identified on the basis of spectral data (MS, 1H-NMR and 13C-NMR).
Twelve compounds were isolated and identified as friedelin (1), 3-oxo-olean-9(11),12-diene (2), canophyllal (3), 3-acetoxy oleanolic acid (4), triptophenolide (5), triptonoterpene methyl ether (6), tricosanoic acid (7), beta-sitosterol (8), stearic acid (9), glut-5-en-3beta,28-diol (10), palmitic acid (11) and daucostorol (12).
Compounds 1, 2, 3, 7 and 10 were isolated from T. hypoglaucum and 7 from the genus Tripterygium for the first time.
研究昆明山海棠根皮的化学成分。
采用硅胶柱色谱和葡聚糖凝胶LH - 20柱色谱分离化合物，并根据光谱数据（质谱、氢核磁共振谱和碳核磁共振谱）鉴定其结构。
分离得到12个化合物，分别鉴定为木栓酮（1）、3 - 氧代 - 齐墩果 - 9(11),12 - 二烯（2）、香楠醇（3）、3 - 乙酰氧基齐墩果酸（4）、雷公藤酚甲（5）、雷公藤三萜甲酯（6）、二十三烷酸（7）、β - 谷甾醇（8）、硬脂酸（9）、谷甾 - 5 - 烯 - 3β,28 - 二醇（10）、棕榈酸（11）和胡萝卜苷（12）。
化合物1、2、3、7和10首次从昆明山海棠中分离得到，化合物7首次从雷公藤属植物中分离得到。
