Department of Pharmaceutical Sciences and University of Connecticut, Storrs, CT 06269, USA.
Pharm Dev Technol. 2012 Mar-Apr;17(2):134-47. doi: 10.3109/10837450.2011.649852. Epub 2012 Jan 19.
This review provides a comprehensive record of experimental and modeling approaches that can be used to study the effect of critical process parameters affecting the coating uniformity in pharmaceutical coating operation. Explicit reference is given to the development of the approach and its previous usage with particular emphasis on the advantages, limitations and model assumptions.
本综述提供了一个全面的记录，介绍了可用于研究影响药物包衣操作中涂层均匀性的关键工艺参数的影响的实验和建模方法。特别提到了该方法的发展及其先前的使用情况，重点介绍了其优点、局限性和模型假设。
