Radwan Walid, Lucke-Wold Brandon, Robadi Ibrahim Ahmed, Gyure Kymberly, Roberts Thomas, Bhatia Sanjay
Department of Neurosurgery, West Virginia University, Morgantown, West Virginia, USA.
West Virginia University, Morgantown, West Virginia, USA.
Postgrad Med J. 2017 Jul;93(1101):401-405. doi: 10.1136/postgradmedj-2016-134475. Epub 2016 Dec 5.
Sarcoidosis is a chronic, multisystem disease characterised by non-necrotising granulomatous inflammation of unknown aetiology. Most commonly, the lungs, lymph nodes, skin and eyes are affected in sarcoidosis; however, nervous system involvement occurs in approximately 5%-15% of cases. Any part of the nervous system can be affected by sarcoidosis.
Herein we describe three unusual patient presentations of neurosarcoidosis, one with optic neuritis, a second with hydrocephalus and a third with cervical myelopathy.
We include pertinent details about their presentations, imaging findings, pathology, management and clinical course.
结节病是一种慢性多系统疾病,其特征为病因不明的非坏死性肉芽肿性炎症。结节病最常累及肺、淋巴结、皮肤和眼睛;然而,约5%-15%的病例会出现神经系统受累。神经系统的任何部位都可能受到结节病的影响。
在此,我们描述三例结节病累及神经系统的不寻常病例,一例为视神经炎,一例为脑积水,另一例为颈髓病。
我们纳入了有关其临床表现、影像学检查结果、病理学、治疗及临床病程的相关细节。