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全身麻醉联合双侧椎旁阻滞(T11 - T12 - L1)与全身麻醉用于双侧精索静脉曲张切除术的比较。一项随机双盲临床试验。

General anaesthesia combined with bilateral paravertebral blockade (T11-T12-L1) vs general anaesthesia for bilateral varicocelectomy. A randomized double-blind clinical trial.

作者信息

Naja Zoher, Al Tannir Mohamad, Naccache Nicole, El Rajab Mariam, Al Sayyid Khaled, Ziade Fouad, Chatila Mohamad

机构信息

Anesthesia & Pain Medicine Department, Makassed General Hospital MGH, Beirut, Lebanon.

出版信息

J Med Liban. 2011 Jul-Sep;59(3):126-30.

PMID:22259899
Abstract

INTRODUCTION

Varicocelectomy is a common operation in urology associated with considerable postoperative pain. The aim of this prospective, randomized, double-blind study was to investigate whether a combination of general anesthesia and bilateral nerve stimulator guided paravertebral nerve blocks could provide better postoperative pain relief compared to general anesthesia in combination with placebo paravertebral nerve block.

METHODS

Sixty patients scheduled for varicocelectomy were randomized prospectively. Thirty patients each in either the active group (general anaesthesia combined with nerve stimulator guided bilateral paravertebral block) or the control group (general anaesthesia combined with normal saline nerve stimulator guided bilateral paravertebral block). Postoperative pain was assessed by visual analogue scale scores at predetermined time intervals.

RESULTS

The active group was found to have better postoperative pain-relief (p < 0.005), reduced need for analgesics (p < 0.05), and also a more rapid return to normal activities (p < 0.001) compared to control group. Higher surgeon and patient satisfaction (p < 0.001) were noted in the active group compared to the control group.

CONCLUSION

Preoperative paravertebral blockade combined with general anesthesia showed significantly reduced postoperative pain scores and analgesic consumption, earlier return to normal activity and was associated with better patient and surgeon satisfaction during varicocelectomy surgery.

摘要

引言

精索静脉曲张切除术是泌尿外科的常见手术,术后疼痛较为明显。本前瞻性、随机、双盲研究旨在探讨全身麻醉联合双侧神经刺激器引导的椎旁神经阻滞与全身麻醉联合安慰剂椎旁神经阻滞相比,是否能提供更好的术后疼痛缓解效果。

方法

60例计划行精索静脉曲张切除术的患者被前瞻性随机分组。活性组(全身麻醉联合神经刺激器引导的双侧椎旁阻滞)和对照组(全身麻醉联合生理盐水神经刺激器引导的双侧椎旁阻滞)各30例。在预定的时间间隔通过视觉模拟量表评分评估术后疼痛。

结果

与对照组相比,活性组术后疼痛缓解更好(p<0.005),镇痛药物需求减少(p<0.05),恢复正常活动也更快(p<0.001)。与对照组相比,活性组外科医生和患者的满意度更高(p<0.001)。

结论

术前椎旁阻滞联合全身麻醉在精索静脉曲张切除术中可显著降低术后疼痛评分和镇痛药物用量,更早恢复正常活动,且患者和外科医生的满意度更高。

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