Division of Endocrinology, Diabetes and Bone Diseases, Mount Sinai School of Medicine, New York, New York 10029–6574, USA.
Curr Opin Endocrinol Diabetes Obes. 2012 Apr;19(2):93-6. doi: 10.1097/MED.0b013e328350583a.
An overview of the global epidemic of diabetes and its impact on the understanding of the disease.
Once thought of as a disease of the West, the prevalence of diabetes mellitus is increasing at alarming rates in many other areas of the world. In recent years, significant attention has been placed on the growing Asian diabetes epidemic. As a result, the medical community has come to understand that previously defined risk factors, particularly BMI, may not be applicable to the global community. The heterogeneity of the disease has been demonstrated both through anthropometric and genetic studies. Despite this heterogeneity, some treatments, particularly lifestyle interventions, have been found to have an ethnic nonspecific positive impact on the disease.
Diabetes promises to become an even larger public health issue with significant social and economic burden with clinical practice and public health policy implications. Further population studies and identification of ethnic specific risk factors will guide research to develop a better understanding of the disease.
全球糖尿病流行情况及其对疾病认识的影响。
糖尿病曾被认为是西方的一种疾病，但在世界许多其他地区，其发病率正以惊人的速度增长。近年来，人们对亚洲糖尿病流行的关注度显著提高。因此，医学界逐渐认识到，以前定义的风险因素，特别是 BMI，可能不适用于全球人群。通过人体测量学和遗传学研究，已经证明了疾病的异质性。尽管存在这种异质性，但一些治疗方法，特别是生活方式干预，已被发现对该疾病具有种族非特异性的积极影响。
糖尿病将成为一个更大的公共卫生问题，对临床实践和公共卫生政策都有重大的社会和经济影响。进一步的人群研究和确定种族特异性的风险因素将指导研究，以更好地了解这种疾病。
