[Changes in the morpho-functional properties of gastric parietal cells during activation of secretory activity].

Electron--microscope and biochemical studies in rats and dogs showed that secretory membranes of parietal cells were in dynamic equilibrium with plasmalemma in activated secretion. During secretion, a transposition of secretory membranes occurs: 53.2% of tubulovesicular membranes transform into membranes of intracellular canaliculi and apical surface. K+--ATPace and carbonic anhydrase activities increased (55.5% and 62.9%, resp.). The system of secretory membranes and enzyme systems of parietal cells seem to take part synchronously in the process of gastric acid secretion.