Moorhead Anita M, Amir Lisa H, O'Brien Paul W, Wong Swee
Royal Women's Hospital, Parkville, Victoria.
Breastfeed Rev. 2011 Nov;19(3):25-9.
Breastfeeding women with continuous burning nipple pain, often associated with post-feed radiating breast pain, may be diagnosed with nipple and breast Candida (thrush) infection. This project examined the efficacy of the three fuconazole capsule regime (one 150 mg capsule alternate days) and explored factors associated with longer courses of fluconazole.
Women diagnosed with nipple and breast Candida and treated with oral fuconazole at a tertiary hospital (n = 96) were followed up until pain resolution.
Women took between 1 and 29 fluconazole capsules, mean = 7.3, median = 6. The number of capsules was not related to socio-demographic or health characteristics of mothers or babies; women with more severe breast pain were more likely to take > 3 capsules than women with less severe breast pain. Only minor side-effects were reported.
Most women require more than three capsules of fluconazole, but two-thirds of women will require six or less.
患有持续性乳头灼痛的哺乳期女性，常伴有喂奶后乳房放射性疼痛，可能被诊断为乳头及乳房念珠菌（鹅口疮）感染。本项目研究了三种氟康唑胶囊治疗方案（隔日服用一粒150毫克胶囊）的疗效，并探讨了与氟康唑疗程较长相关的因素。
在一家三级医院被诊断为乳头及乳房念珠菌感染并接受口服氟康唑治疗的女性（n = 96），随访至疼痛缓解。
女性服用氟康唑胶囊的数量在1至29粒之间，平均为7.3粒，中位数为6粒。胶囊数量与母亲或婴儿的社会人口统计学或健康特征无关；乳房疼痛较严重的女性比疼痛较轻的女性更有可能服用超过3粒胶囊。仅报告了轻微的副作用。
大多数女性需要服用超过三粒氟康唑胶囊，但三分之二的女性需要六粒或更少。
