Kapdi Muznah, Shah Ira
Department of Pediatrics, B.J. Wadia Hospital for Children, Mumbai, India.
Scand J Infect Dis. 2012 Sep;44(9):708-9. doi: 10.3109/00365548.2011.652667. Epub 2012 Jan 21.
Dengue is characterized by biphasic fever, myalgia or arthralgia, rash, leukopenia, and lymphadenopathy. It is self-limiting, and dengue-associated haemophagocytic lymphohistiocytosis has been reported in fewer than 20 children worldwide. We report the case of a 4-y-old boy with dengue who continued to have fever for 30 days, with hepatomegaly, thrombocytopenia, and leukopenia. Bone marrow examination showed haemophagocytes. The child was treated with steroids, instead etoposide and oral cyclosporine.
登革热的特征为双相热、肌痛或关节痛、皮疹、白细胞减少和淋巴结病。它是自限性疾病，全球范围内报告的与登革热相关的噬血细胞性淋巴组织细胞增生症患儿不到20例。我们报告了一名4岁登革热患儿的病例，该患儿持续发热30天，伴有肝肿大、血小板减少和白细胞减少。骨髓检查显示有噬血细胞。该患儿接受了类固醇治疗，而非依托泊苷和口服环孢素。
