Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, UT, USA.
J Neurosurg. 2012 Apr;116(4):861-5. doi: 10.3171/2011.12.JNS111020. Epub 2012 Jan 20.
Myxoid (metaplastic) meningioma is a rare WHO Grade I meningioma subtype arising from the leptomeninges. It has unique Alcian blue stromal staining and distinctive cellular interdigitations, junctional complexes, and nucleolar pseudoinclusions on ultrastructural pathology that help to distinguish it from other meningioma variants. The authors describe the case of a rare left middle fossa, extraaxial myxoid meningioma in a 50-year-old woman to emphasize the important histological characteristics and observations essential for making a precise diagnosis. To their knowledge this is the seventh reported case of a myxoid meningioma in the literature and the sixth case in an adult; however, it is the first reported instance of myxoid meningioma in a patient presenting with intratumoral hemorrhage.
黏液样（化生型）脑膜瘤是一种罕见的起源于软脑膜的 WHO 分级 I 型脑膜瘤亚型。它具有独特的阿尔辛蓝基质染色和独特的细胞交错、连接复合体和核仁假包涵体，这些在超微结构病理学上有助于将其与其他脑膜瘤变体区分开来。作者描述了一例罕见的左中颅窝、外轴黏液样脑膜瘤，患者为 50 岁女性，旨在强调做出准确诊断所需的重要组织学特征和观察。据作者所知，这是文献中第七例报告的黏液样脑膜瘤病例，也是第六例成人病例；然而，这是首例报告的黏液样脑膜瘤病例，患者表现为肿瘤内出血。
