Department of Neurosurgery, Kanazawa Medical University, 1-1 Daigaku, Uchinada 920-0293, Ishikawa, Japan.
J Clin Neurosci. 2013 Nov;20(11):1622-4. doi: 10.1016/j.jocn.2012.11.023. Epub 2013 Jul 27.
Oncocytic meningiomas have been recently reported as a rare variant of meningiomas. Immunohistochemical analysis shows that neoplastic cells are positive for antimitochondrial antibodies. We report our first patient with oncocytic meningioma, presenting with intratumoral bleeding. A 72-year-old woman suffered from a disturbance of consciousness. A CT scan showed a tumor with intratumoral hemorrhage. An emergency craniotomy was performed and the tumor and hematoma were removed. Examination of the tumor revealed meningothelial cells with oncocytic change. We discuss the clinicopathological considerations of this uncommon variant and review the pertinent literature.
近年来，有报道称嗜酸细胞瘤是脑膜瘤的一种罕见变体。免疫组织化学分析显示，肿瘤细胞对抗线粒体抗体呈阳性。我们报告了首例伴有嗜酸细胞瘤的脑膜瘤患者，其表现为肿瘤内出血。一名 72 岁女性出现意识障碍。CT 扫描显示肿瘤内有出血。紧急开颅手术切除肿瘤和血肿。肿瘤检查显示脑膜上皮细胞伴有嗜酸细胞瘤改变。我们讨论了这种罕见变体的临床病理考虑，并复习了相关文献。
