Department of Physical Medicine and Rehabilitation, Taipei Medical University Hospital, Taiwan.
Am J Cardiol. 2012 Apr 15;109(8):1160-3. doi: 10.1016/j.amjcard.2011.11.056. Epub 2012 Jan 19.
The aim of the present study was to explore the outcomes of percutaneous coronary intervention (PCI) in patients with rheumatoid arthritis (RA) and coronary heart disease. We identified 25,367 patients from the National Health Insurance Research Database who underwent nonstenting PCI in Taiwan in 2007. Of these patients, 240 had been diagnosed with RA. As a comparison group, we selected 1,200 patients who were matched with the study group by gender and age. We performed conditional logistic regression analysis to compare the outcomes of PCI between the 2 groups. We found no significant differences in the rates of in-hospital mortality (2.5% vs 3.1%, p = 0.628), 90-day readmission for PCI (8.3% vs 7.2%, p = 0.559), or 365-day readmission for PCI (22.5% vs 19.2%, p = 0.236) between the patients with and without RA. Similarly, the conditional logistic regression analyses revealed that patients with RA had no greater adjusted odds of in-hospital mortality (odds ratio 0.94, 95% confidence interval 0.37 to 2.36), 90-day readmission for PCI (odds ratio 1.20, 95% confidence interval 0.37 to 2.36), and 365-day readmission for PCI (odds ratio 1.30, 95% confidence interval 0.92 to 1.83) than the comparison group. In conclusion, our study did not find an increased risk of adverse outcomes among patients with RA after PCI.
本研究旨在探讨类风湿关节炎（RA）合并冠心病患者经皮冠状动脉介入治疗（PCI）的结局。我们从台湾地区 2007 年国家健康保险研究数据库中确定了 25367 例接受非支架 PCI 的患者。其中 240 例被诊断为 RA。作为对照组，我们选择了 1200 名与研究组性别和年龄匹配的患者。我们进行条件 logistic 回归分析，比较两组患者 PCI 的结局。我们发现两组患者住院期间死亡率（2.5%比 3.1%，p = 0.628）、90 天 PCI 再入院率（8.3%比 7.2%，p = 0.559）或 365 天 PCI 再入院率（22.5%比 19.2%，p = 0.236）均无显著差异。同样，条件 logistic 回归分析显示，RA 患者住院期间死亡率（优势比 0.94，95%置信区间 0.37 至 2.36）、90 天 PCI 再入院率（优势比 1.20，95%置信区间 0.37 至 2.36）和 365 天 PCI 再入院率（优势比 1.30，95%置信区间 0.92 至 1.83）的调整比值均无显著增加。总之，我们的研究并未发现 RA 患者 PCI 后不良结局的风险增加。
