Department of Chemical Engineering, National Taiwan University, Taipei, Taiwan.
Colloids Surf B Biointerfaces. 2012 May 1;93:154-60. doi: 10.1016/j.colsurfb.2011.12.031. Epub 2012 Jan 2.
The importance of the porous structure of a soft particle comprising a rigid core and a porous layer on its electrophoretic behavior is investigated. The porous layer is simulated by an aggregate of primary units, rendering it to have a radially varying fixed charge and hydrodynamic resistance. Key factors, including the thickness of double layer, the linear size of a primary unit, the aggregate dimension, and the thickness and the fixed charge density of the porous layer, are examined for their influence on the mobility of a particle. We show that if the fixed charge density is fixed, then the mobility increases with increasing double layer thickness, and the mobility increases with increasing fixed charge density. Increasing the linear size of a primary unit raises appreciably the mobility. In addition, the mobility increases with increasing thickness or aggregate dimension of the porous layer. The structure of the porous layer of a particle affects most significantly its mobility when the double layer is thick.
研究了由刚性核和多孔层组成的软颗粒的多孔结构对其电泳行为的重要性。多孔层通过初级单元的聚集体来模拟，使其具有径向变化的固定电荷和流体动力阻力。考察了关键因素，包括双层厚度、初级单元的线性尺寸、聚集体尺寸以及多孔层的厚度和固定电荷密度，它们对颗粒迁移率的影响。结果表明，如果固定电荷密度固定，则迁移率随双层厚度的增加而增加，且迁移率随固定电荷密度的增加而增加。增加初级单元的线性尺寸会显著提高迁移率。此外，随着多孔层的厚度或聚集体尺寸的增加，迁移率也会增加。当双层较厚时，颗粒多孔层的结构对其迁移率的影响最大。
