Department of Mathematics, Tamkang University, Tamsui, Taipei, 25137, Taiwan.
Colloids Surf B Biointerfaces. 2013 Feb 1;102:864-70. doi: 10.1016/j.colsurfb.2012.09.014. Epub 2012 Sep 14.
The importance of the effective membrane charge on the electrophoretic behavior of a soft spherical particle comprising a rigid core and a charge-regulated membrane layer, mimicking both inorganic and biological colloids, is investigated. The mobility of the particle is simulated under various conditions by varying the double layer thickness, the bulk solution pH, and the charged conditions of the membrane layer. Several interesting electrophoretic behaviors that are of practical significance, are observed. For example, the particle mobility can be controlled by adjusting its properties such as the ratios of (acidic equilibrium constant/basic equilibrium constant) and (concentration of acidic functional groups/that of basic functional groups). Double layer polarization (DLP) is found to render the soft particle having behaviors different from those of the corresponding rigid particle. For instance, DLP can either be intensified or weakened, depending upon the strength of the hydrodynamic force and the electric force acting on the membrane layer. As the bulk electrolyte concentration increases in a certain range, because double layer shrinks into the membrane layer, its effective charge density increases, so is the particle mobility.
研究了具有刚性核和电荷调节膜层的软球形粒子（模拟无机和生物胶体）的有效膜电荷对电泳行为的重要性。通过改变双层厚度、本体溶液 pH 值和膜层带电条件，模拟了在各种条件下粒子的迁移率。观察到了几种具有实际意义的有趣电泳行为。例如，可以通过调整粒子的性质（例如（酸性平衡常数/碱性平衡常数）和（酸性官能团浓度/碱性官能团浓度）的比值）来控制粒子的迁移率。发现双层极化（DLP）使软粒子具有与相应刚性粒子不同的行为。例如，根据作用在膜层上的流体动力和电力的强度，DLP 可以增强或减弱。随着本体电解质浓度在一定范围内增加，由于双层收缩到膜层中，其有效电荷密度增加，因此粒子迁移率也增加。
