Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0526, USA.
Am J Obstet Gynecol. 2012 Mar;206(3):259.e1-6. doi: 10.1016/j.ajog.2011.12.017. Epub 2011 Dec 24.
We sought to quantify the gestational age-specific morbidity of black vs white neonates.
This was a population-based retrospective cohort study of singleton live births in Ohio from 2006 through 2007. The primary outcome was a composite of adverse neonatal outcomes of ≥ 1 morbidity: Apgar score < 7 at 5 minutes, assisted ventilation > 6 hours, seizures, or neonatal transport to a tertiary care facility. Generalized linear regression estimated the relative risk of adverse neonatal outcome by week of gestation after adjustment for influential coexistent risk factors.
The frequency distribution curve of composite morbidity by gestational age were similar, but shifted to left (earlier gestational age) for black compared with white neonates. Adverse outcome was lower for black compared with white births at each preterm week of gestational age. The lowest adverse outcome rate for black neonates was at 38 weeks and 39 weeks for white neonates, each increasing by week of gestation thereafter.
These data suggest that pregnancies in black women perhaps have a shorter physiologic gestational length.
我们旨在量化黑种与白种新生儿特定胎龄的发病情况。
这是一项基于人群的回顾性队列研究,纳入了 2006 年至 2007 年俄亥俄州的单胎活产儿。主要结局是≥1 种不良新生儿结局的复合指标:5 分钟时 Apgar 评分<7 分、辅助通气>6 小时、癫痫发作或新生儿转运至三级医疗保健机构。广义线性回归在调整了潜在共存的危险因素后,估计了胎龄周数与不良新生儿结局的相对风险。
胎龄特异性复合发病情况的频率分布曲线相似,但黑人新生儿的曲线向左(胎龄更早)偏移。与白人新生儿相比,每个早产胎龄的黑人新生儿不良结局的发生率较低。黑人新生儿的最低不良结局发生率出现在 38 周和 39 周,此后每增加一周,发生率都会增加。
这些数据表明,黑人孕妇的妊娠可能具有较短的生理性妊娠时间。