Key Laboratory of Applied Technology of Marine Biology, Ministry of Education, Ningbo University, 818 Fenghua Road, Ningbo 315211, China.
J Chromatogr A. 2012 Mar 2;1227:60-6. doi: 10.1016/j.chroma.2012.01.012. Epub 2012 Jan 11.
Two types of molecularly imprinted polymers (MIPs) for the simultaneous determination of six pyrethroid insecticides have been developed using deltamethrin (D-MIPs) and cypermethrin (C-MIPs) as template molecules. A comparison of the performance of D-MIPs, C-MIPs, and the corresponding non-imprinted polymers (NIPs) were conducted. Stronger group-selective interactions between the C-MIPs and the six pyrethroid insecticides were achieved. The MISPE method based on the C-MIPs displayed higher extraction recoveries (86.4-96.0%) with RSD values ranging from 2.4 to 7.8% for the six pyrethroid insecticides in aquaculture seawater. After the C-MIP cartridge procedure, the limits of detection and quantification for fenvalerate, deltamethrin, cypermethrin, cyfluthrin, and bifenthrin were in the 16.6-37.0 and 55.3-109.1 ng L⁻¹ ranges, respectively, and 0.68 and 2.26 μg L⁻¹ for phenothrin, respectively. The proposed MISPE method coupled with gas chromatography-electron capture detection was successfully used for the determination of the six pyrethroid insecticides in aquaculture seawater.
两种分子印迹聚合物（MIPs）已被开发用于同时测定六种拟除虫菊酯类杀虫剂，其中使用氯菊酯（D-MIPs）和氯氰菊酯（C-MIPs）作为模板分子。对 D-MIPs、C-MIPs 和相应的非印迹聚合物（NIPs）的性能进行了比较。C-MIPs 与六种拟除虫菊酯类杀虫剂之间实现了更强的基团选择性相互作用。基于 C-MIPs 的 MISPE 方法在养殖海水中对六种拟除虫菊酯类杀虫剂的提取回收率（86.4-96.0%）较高，相对标准偏差（RSD）值为 2.4-7.8%。经过 C-MIP 柱处理程序后，对氰戊菊酯、氯菊酯、氯氰菊酯、氟氯氰菊酯和溴氰菊酯的检测限和定量限分别在 16.6-37.0 和 55.3-109.1 ng L⁻¹范围内，对苯醚菊酯的检测限和定量限分别为 0.68 和 2.26 μg L⁻¹。所提出的 MISPE 方法与气相色谱-电子捕获检测相结合，成功地用于养殖海水中六种拟除虫菊酯类杀虫剂的测定。
