Doré B, Irani J, Aubert J
Urology Department, University of Poitiers, France.
Eur Urol. 1990;18(2):153-5. doi: 10.1159/000463895.
Three cases of glans penis epidermoid carcinoma after lichen sclerosus et atrophicus (LSA) or balanitis xerotica obliterans are discussed. Relationships between both diseases are analyzed but remain unclear. Balanitis xerotica obliterans causes foreskin and urethral meatus stenosis that requires circumcision. Glans penis carcinoma can be observed many years later even after circumcision. The knowledge of LSA is important to do circumcision at the beginning of the disease with a long-term follow-up of these patients to realize a glans penis biopsy if necessary. Most cases of LSA are not recognized, and the frequency is higher than reported.
本文讨论了3例硬化性萎缩性苔藓（LSA）或闭塞性干燥性龟头炎后发生的阴茎头表皮样癌。分析了这两种疾病之间的关系，但仍不明确。闭塞性干燥性龟头炎会导致包皮和尿道口狭窄，需要进行包皮环切术。即使在包皮环切术后多年，仍可观察到阴茎头癌。了解LSA对于在疾病初期进行包皮环切术并对这些患者进行长期随访以便在必要时进行阴茎头活检非常重要。大多数LSA病例未被识别，其发生率高于报道的数字。
