• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

阴茎皮肤病:一项临床与组织病理学研究。

Penile dermatoses: a clinical and histopathological study.

作者信息

Hillman R J, Walker M M, Harris J R, Taylor-Robinson D

机构信息

Division of Sexually Transmitted Diseases, Clinical Research Centre, Harrow, Middlesex, UK.

出版信息

Genitourin Med. 1992 Jun;68(3):166-9. doi: 10.1136/sti.68.3.166.

DOI:10.1136/sti.68.3.166
PMID:1607192
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1194848/
Abstract

OBJECTIVE

To assess the spectrum of genital dermatological conditions affecting men and compare the clinical and histopathological diagnoses.

DESIGN

Prospective study over a one year period.

SETTING

A central London teaching hospital.

PATIENTS

Seventy one patients with unresponsive penile dermatoses attending a specific internal referral clinic within the department of genitourinary medicine and 36 patients undergoing penile biopsy following attendance at other departments within the same hospital.

METHODS

Full dermatological assessment of patients attending the specific clinic. Standard histopathological methods were used in the diagnosis of biopsy specimens.

OUTCOME MEASURED

Clinico-pathological diagnosis of cutaneous penile abnormalities.

RESULTS

Description of the range and relative frequency of penile dermatological conditions. The most common histopathological diagnosis was of non specific dermatitis. Twenty seven percent (16 of 61) of patients attending the specific clinic and 33% (12 of 36) of men attending other departments had conditions requiring long term follow up.

CONCLUSIONS

The ranges of penile dermatoses presenting to the different departments were broadly similar. Penile biopsy was shown to be a safe and clinically informative procedure. In the genitourinary clinic setting, clinical diagnosis prior to biopsy was found frequently to be inaccurate.

摘要

目的

评估影响男性的生殖器皮肤病谱,并比较临床诊断与组织病理学诊断。

设计

为期一年的前瞻性研究。

地点

伦敦市中心的一家教学医院。

患者

71例患有顽固性阴茎皮肤病的患者,他们在泌尿生殖医学科的一个特定内部转诊诊所就诊,以及36例在同一家医院的其他科室就诊后接受阴茎活检的患者。

方法

对在特定诊所就诊的患者进行全面的皮肤病学评估。活检标本的诊断采用标准组织病理学方法。

测量指标

阴茎皮肤异常的临床病理诊断。

结果

描述阴茎皮肤病的范围和相对频率。最常见的组织病理学诊断是非特异性皮炎。在特定诊所就诊的患者中有27%(61例中的16例),在其他科室就诊的男性中有33%(36例中的12例)患有需要长期随访的疾病。

结论

不同科室出现的阴茎皮肤病谱大致相似。阴茎活检被证明是一种安全且具有临床指导意义的操作。在泌尿生殖诊所环境中,发现活检前的临床诊断常常不准确。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1204/1194848/4e873f00e107/genitmed00033-0021-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1204/1194848/4e873f00e107/genitmed00033-0021-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1204/1194848/4e873f00e107/genitmed00033-0021-a.jpg

相似文献

1
Penile dermatoses: a clinical and histopathological study.阴茎皮肤病:一项临床与组织病理学研究。
Genitourin Med. 1992 Jun;68(3):166-9. doi: 10.1136/sti.68.3.166.
2
Role of penile biopsy in the diagnosis of penile dermatoses.阴茎活检在阴茎皮肤病诊断中的作用。
Int J STD AIDS. 2010 May;21(5):371-2. doi: 10.1258/ijsa.2010.009568.
3
Efficacy and safety of penile biopsy in a GUM clinic setting.
Int J STD AIDS. 2002 Aug;13(8):573-6. doi: 10.1258/095646202760159729.
4
The value of a multi-specialty service, including genitourinary medicine, dermatology and urology input, in the management of male genital dermatoses.多专科服务(包括性传播感染科、皮肤科和泌尿科的投入)在男性生殖器皮肤病管理中的价值。
Int J STD AIDS. 2015 Sep;26(10):716-22. doi: 10.1177/0956462414552695. Epub 2014 Oct 6.
5
Dermatoses of the glans penis and prepuce.阴茎头和包皮皮肤病
J Am Acad Dermatol. 1997 Jul;37(1):1-24; quiz 25-6. doi: 10.1016/s0190-9622(97)70207-x.
6
[Penile dermatoses].[阴茎皮肤病]
Urologe A. 2015 May;54(5):684-9. doi: 10.1007/s00120-015-3798-z.
7
Penile skin diseases.阴茎皮肤疾病。
Andrologia. 1999;31 Suppl 1:3-11. doi: 10.1111/j.1439-0272.1999.tb01443.x.
8
Common genital dermatoses in male patients attending a public sexually transmitted disease clinic in Singapore.新加坡一家公立性传播疾病诊所男性患者常见的生殖器皮肤病。
Ann Acad Med Singap. 1995 Jul;24(4):505-9.
9
[The value of biopsy in the diagnosis of penile dermatoses].[活检在阴茎皮肤病诊断中的价值]
Ann Dermatol Venereol. 2012 Aug-Sep;139(8-9):521-5. doi: 10.1016/j.annder.2012.04.152. Epub 2012 May 31.
10
The acetic acid test in evaluation of subclinical genital papillomavirus infection: a comparative study on penoscopy, histopathology, virology and scanning electron microscopy findings.醋酸试验在亚临床生殖器乳头瘤病毒感染评估中的应用:一项关于阴道镜检查、组织病理学、病毒学及扫描电子显微镜检查结果的对比研究
Genitourin Med. 1992 Apr;68(2):90-9. doi: 10.1136/sti.68.2.90.

引用本文的文献

1
Prevalence of nonvenereal genital dermatoses in patients attending tertiary care center.三级护理中心就诊患者中非性病性生殖器皮肤病的患病率。
Indian J Sex Transm Dis AIDS. 2025 Jan-Jun;46(1):52-57. doi: 10.4103/ijstd.ijstd_58_25. Epub 2025 Jun 9.
2
Dermatoses of the Glans Penis in Korea: A 10-Year Single Center Experience.韩国阴茎头皮肤病:一项为期10年的单中心经验
Ann Dermatol. 2016 Feb;28(1):40-4. doi: 10.5021/ad.2016.28.1.40. Epub 2016 Jan 28.
3
A study of pattern of nonvenereal genital dermatoses of male attending skin OPD at a tertiary care center.

本文引用的文献

1
In vitro antibacterial activity of different clotrimazole formulations.不同克霉唑制剂的体外抗菌活性
Chemotherapy. 1982;28 Suppl 1:32-6. doi: 10.1159/000238149.
2
Laboratory assessment of the antimycotic drug clotrimazole.抗真菌药物克霉唑的实验室评估。
J Clin Pathol. 1972 Dec;25(12):1089-97. doi: 10.1136/jcp.25.12.1089.
3
High prevalence of papillomavirus-associated penile intraepithelial neoplasia in sexual partners of women with cervical intraepithelial neoplasia.宫颈上皮内瘤变女性性伴侣中乳头瘤病毒相关阴茎上皮内瘤变的高患病率。
一项针对三级医疗中心皮肤科门诊男性非性病性生殖器皮肤病模式的研究。
Indian J Sex Transm Dis AIDS. 2014 Jul-Dec;35(2):129-34. doi: 10.4103/0253-7184.142408.
4
[Genital dermatoses: epidemiological and clinical profile].[生殖器皮肤病:流行病学和临床概况]
Pan Afr Med J. 2014 Jul 23;18:240. doi: 10.11604/pamj.2014.18.240.4797. eCollection 2014.
5
Balanitis and balanoposthitis: a review.龟头炎和阴茎头炎:综述
Genitourin Med. 1996 Jun;72(3):155-9. doi: 10.1136/sti.72.3.155.
6
Candidal balano-posthitis: a study of diagnostic methods.念珠菌性龟头包皮炎:诊断方法研究
Genitourin Med. 1995 Dec;71(6):407-9. doi: 10.1136/sti.71.6.407.
7
Changes in HPV infection in patients with anogenital warts and their partners.肛门生殖器疣患者及其性伴的人乳头瘤病毒感染变化
Genitourin Med. 1993 Dec;69(6):450-6. doi: 10.1136/sti.69.6.450.
8
Clinical features and management of recurrent balanitis; association with atopy and genital washing.复发性龟头炎的临床特征与管理;与特应性及生殖器清洗的关联
Genitourin Med. 1993 Oct;69(5):400-3. doi: 10.1136/sti.69.5.400.
9
Papillomavirus-associated balanoposthitis.人乳头瘤病毒相关性阴茎头炎
Genitourin Med. 1994 Jun;70(3):175-81. doi: 10.1136/sti.70.3.175.
N Engl J Med. 1987 Oct 8;317(15):916-23. doi: 10.1056/NEJM198710083171502.
4
The association of lichen planus of the penis with squamous cell carcinoma in situ and with verrucous squamous carcinoma.阴茎扁平苔藓与原位鳞状细胞癌及疣状鳞状癌的关联。
J Dermatol Surg Oncol. 1989 Apr;15(4):413-7. doi: 10.1111/j.1524-4725.1989.tb03247.x.
5
Characterization of intercellular adhesion molecule-1 and HLA-DR expression in normal and inflamed skin: modulation by recombinant gamma interferon and tumor necrosis factor.正常皮肤和炎症皮肤中细胞间黏附分子-1及人类白细胞抗原-DR表达的特征:重组γ干扰素和肿瘤坏死因子的调节作用
J Am Acad Dermatol. 1989 Apr;20(4):617-29. doi: 10.1016/s0190-9622(89)70073-6.
6
Value of performing biopsies in genitourinary clinics.在泌尿生殖科诊所进行活检的价值。
Genitourin Med. 1990 Oct;66(5):407. doi: 10.1136/sti.66.5.407.
7
Carcinoma of the penis in lichen sclerosus atrophicus. A case report.萎缩性硬化性苔藓中的阴茎癌。病例报告。
Eur Urol. 1990;18(2):153-5. doi: 10.1159/000463895.
8
Chronic erosive vulval disease.
Clin Exp Dermatol. 1990 Jul;15(4):245-52. doi: 10.1111/j.1365-2230.1990.tb02083.x.
9
The epithelial changes associated with squamous cell carcinoma of the vulva: a review of the clinical, histological and viral findings in 78 women.外阴鳞状细胞癌相关的上皮变化:78例女性患者临床、组织学及病毒学检查结果综述
Br J Obstet Gynaecol. 1990 Dec;97(12):1135-9. doi: 10.1111/j.1471-0528.1990.tb02502.x.
10
Carcinoma of the penis developed in lichen sclerosus et atrophicus.阴茎癌发生于硬化性萎缩性苔藓。
Br J Vener Dis. 1978 Oct;54(5):350-1. doi: 10.1136/sti.54.5.350.