Torebjörk H E, Ochoa J L
Department of Clinical Neurophysiology, University Hospital, Uppsala, Sweden.
Exp Brain Res. 1990;81(3):509-14. doi: 10.1007/BF02423499.
A new technique is described for detecting nociceptor activity in microelectrode recordings from cutaneous fascicles of the human median nerve. The search strategy involves combined intraneural microstimulation and microneurographic recording in intrafascicular sites, where a critically low electrical stimulus amplitude evokes a threshold sensation of pain. From the subject's projection of pain to a small area of skin, the experimenter is guided to receptive fields of recordable nociceptor units. This technique has allowed, for the first time, to identify and study receptive properties of very high threshold nociceptors with A and C fibers in the glabrous skin of the human hand.
本文描述了一种新技术，用于在人正中神经皮束的微电极记录中检测伤害感受器的活动。搜索策略包括在束内部位进行神经内微刺激和微神经图记录相结合，在该部位极低的电刺激幅度会引发疼痛的阈值感觉。根据受试者将疼痛投射到一小块皮肤区域，实验者可被引导至可记录的伤害感受器单位的感受野。这项技术首次使得识别和研究人手无毛皮肤中具有A纤维和C纤维的极高阈值伤害感受器的感受特性成为可能。
