Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
J Acquir Immune Defic Syndr. 2012 May 1;60(1):77-82. doi: 10.1097/QAI.0b013e318249fe90.
Monitoring immunologic and virologic responses to antiretroviral therapy in HIV-1-infected patients is an important component of treatment in the United States. However, little population-based information is available on whether HIV-infected persons receive the recommended tests or continuous care.
Using data from 13 areas reporting relevant HIV-related tests to national HIV surveillance, we determined retention in care in persons older than 12 years living with HIV at the end of 2009. We assessed retention in care, defined as ≥2 CD4 or viral load tests at least 3 months apart in the past year, by demographic, clinical, and risk characteristics and calculated prevalence ratios and 95% confidence intervals. We also assessed the percentage established in care within 12 months after HIV diagnosis in 2008 (≥2 tests, ≥3 months apart).
Among 100,375 persons living with HIV, 45% had ≥2 tests at least 3 months apart. A higher percentage of whites were retained in care (50%) compared with blacks/African Americans (41%, prevalence ratio: 0.83, 95% confidence interval: 0.82 to 0.84) and Hispanics/Latinos (40%, prevalence ratio: 0.90, 95% CI: 0.87 to 0.92). Compared with heterosexual women (50%), fewer men who have sex with men (48%), heterosexual men (45%), and male (37%) and female (43%) injection drug users had ≥2 tests. Approximately 64% established care within 12 months of diagnosis.
Less than half of persons living with HIV had laboratory evidence of ongoing clinical care and only two thirds established care after diagnosis. Further assessments determining modifiable barriers to accessing care could assist with achieving public health targets.
监测艾滋病毒感染者的免疫和病毒学反应是美国治疗的一个重要组成部分。然而,关于艾滋病毒感染者是否接受了推荐的检测或持续护理,几乎没有基于人群的信息。
我们使用向国家艾滋病毒监测报告相关艾滋病毒相关检测的 13 个地区的数据,确定了在 2009 年底患有艾滋病毒的 12 岁以上患者的护理保留率。我们根据人口统计学、临床和风险特征评估了过去一年中至少相隔 3 个月进行了 2 次以上 CD4 或病毒载量检测的护理保留情况,并计算了患病率比和 95%置信区间。我们还评估了 2008 年在诊断后 12 个月内(至少相隔 2 次,至少相隔 3 个月)建立护理的百分比。
在 100375 名艾滋病毒感染者中,有 45%的人至少相隔 3 个月进行了 2 次以上的检测。与黑人/非裔美国人(41%,患病率比:0.83,95%置信区间:0.82 至 0.84)和西班牙裔/拉丁裔(40%,患病率比:0.90,95%置信区间:0.87 至 0.92)相比,白人患者的护理保留率更高。与异性恋女性(50%)相比,男男性接触者(48%)、异性恋男性(45%)和男性(37%)和女性(43%)注射吸毒者的检测次数较少。大约 64%的人在诊断后 12 个月内建立了护理。
不到一半的艾滋病毒感染者有实验室证据表明他们正在接受临床护理,只有三分之二的人在诊断后建立了护理。进一步评估确定获得护理的可改变障碍,可以帮助实现公共卫生目标。