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SLC6A4基因5-HTTLPR多态性与运动员力竭运动期间简单和复杂反应时间参数及临界闪烁频率阈值的关联

Association of SLC6A4 gene 5-HTTLPR polymorphism with parameters of simple and complex reaction times and critical flicker frequency threshold in athletes during exhaustive exercise.

作者信息

Trushkin E V, Timofeeva M A, Sysoeva O V, Davydov Y I, Knicker A, Struder H, Tonevitsky A G

机构信息

Russian Research Institute of Sport and Physical Education, Moscow, Russia.

出版信息

Bull Exp Biol Med. 2011 Feb;150(4):471-4. doi: 10.1007/s10517-011-1171-9.

DOI:10.1007/s10517-011-1171-9
PMID:22268046
Abstract

The incidence of SLC6A4 gene 5HTTLPR polymorphism alleles was evaluated in 223 male athletes engaged in endurance sports, the results were compared with those in 177 male nonathletes. Association between 5-HTTLPR genotypes and the effect of exhaustive treadmill running on simple and complex visual reactions and critical flicker frequency threshold was studied. We found that the incidence of LL genotype was significantly higher in athletes in comparison to nonathletes; after exercise, the velocity of visual reactions and critical flicker frequency increased; exercise did not change the velocity of complex visual reaction in LL-carriers, and increased it in SS-carriers. We conclude that exhausting treadmill running leads to facilitation sensory information processing in athletes and that SS-carriers are more susceptible to the effect of exhaustive treadmill running than LL-carriers.

摘要

对223名从事耐力运动的男性运动员的SLC6A4基因5HTTLPR多态性等位基因发生率进行了评估,并将结果与177名男性非运动员进行了比较。研究了5-HTTLPR基因型与力竭性跑步机跑步对简单和复杂视觉反应及临界闪烁频率阈值影响之间的关联。我们发现,与非运动员相比,运动员中LL基因型的发生率显著更高;运动后,视觉反应速度和临界闪烁频率增加;运动并未改变LL基因型携带者的复杂视觉反应速度,但增加了SS基因型携带者的复杂视觉反应速度。我们得出结论,力竭性跑步机跑步可促进运动员的感觉信息处理,且SS基因型携带者比LL基因型携带者更易受跑步机力竭运动的影响。

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