Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.
AJNR Am J Neuroradiol. 2012 May;33(5):858-64. doi: 10.3174/ajnr.A2862. Epub 2012 Jan 19.
SWI is a unique pulse sequence sensitive to both hemorrhage and calcification. Our aim was to retrospectively assess the ability of SWI to detect intratumoral calcification in ODs compared with conventional MR imaging.
Using CT as criterion standard, the MR imaging findings from 71 patients (33 males, 38 females; mean age, 42.5 years) with pathologically proved OD were retrospectively evaluated. We classified the MR imaging data into SWI data (MRSWI) and traditional pulse sequences (MRnoSWI). The sensitivity and specificity of the MRnoSWI (n = 71) were compared with that of the MRSWI (n = 13) independently and also for matched-paired data (n = 13). The Fisher exact test was applied to the matched-pair data for statistical evaluation.
For paired data of MRSWI and MRnoSWI (n = 13), there was significantly increased sensitivity of MRSWI (86%) for the detection of intratumoral calcification in OD compared with the MRnoSWI (14.3%) (P = .015, Fisher exact test) by using CT as the criterion standard. The overall accuracy of MRSWI for the paired data was also significantly greater (P = .048). The specificities were not significantly different (P = .773). The sensitivity of MRSWI (n = 13) was 86%, and for MRnoSWI (n = 71), it was 33.3%. Specificity of MRSWI was 83%, and for MRnoSWI, it was 95%.
SWI is better able to detect calcification in ODs than conventional MR imaging pulse sequences.
SWI 是一种对出血和钙化均敏感的独特脉冲序列。我们旨在回顾性评估 SWI 检测颅内肿瘤钙化的能力，并与常规磁共振成像（MR）进行比较。
使用 CT 作为标准，回顾性评估了 71 例经病理证实的颅内肿瘤患者（33 名男性，38 名女性；平均年龄 42.5 岁）的 MR 成像结果。我们将 MR 成像数据分为 SWI 数据（MRSWI）和传统脉冲序列（MRnoSWI）。独立评估并比较了 71 例 MRnoSWI（n=71）和 13 例 MRSWI（n=13）的敏感性和特异性，同时还对配对数据（n=13）进行了评估。Fisher 确切检验用于配对数据的统计评估。
对于 MRSWI 和 MRnoSWI 的配对数据（n=13），使用 CT 作为标准，MRSWI 检测颅内肿瘤钙化的敏感性（86%）明显高于 MRnoSWI（14.3%）（P=0.015，Fisher 确切检验）。配对数据的 MRSWI 总体准确性也显著更高（P=0.048）。特异性无显著差异（P=0.773）。MRSWI 的敏感性（n=13）为 86%，MRnoSWI 的敏感性（n=71）为 33.3%。MRSWI 的特异性为 83%，MRnoSWI 的特异性为 95%。
SWI 比常规 MR 成像脉冲序列更能检测颅内肿瘤中的钙化。
