Tejada M I, Mendoza R, Carbonero K, Lizarraga M A, Escudero F, Benito J A
Department of Obstetrics and Gynecology, Hospital de Cruces, Baracaldo, Vizcaya, Spain.
Fertil Steril. 1990 Nov;54(5):953-4. doi: 10.1016/s0015-0282(16)53967-3.
It seems that assisted reproduction technology does not increase the rate of chromosome abnormalities, and up to now, a few cases have been reported. The case we describe here is the first one of monosomy 4q31 in a full-term liveborn after a combined GIFT-IVF procedure. Once more, this case raises the question of whether pregnancies resulting from IVF should be monitored for chromosome abnormalities or not.
辅助生殖技术似乎并不会增加染色体异常的发生率，截至目前，仅有少数病例报道。我们在此描述的病例是首例经配子输卵管内移植（GIFT）与体外受精（IVF）联合治疗后足月活产的4号染色体长臂31区单体病例。此病例再次引发了关于对IVF妊娠是否应监测染色体异常的问题。
