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坦桑尼亚西北部布甘多医疗中心的脾损伤:一家三级医院的经验。

Splenic injuries at Bugando Medical Centre in northwestern Tanzania: a tertiary hospital experience.

作者信息

Chalya Phillipo L, Mabula Joseph B, Giiti Geofrey, Chandika Alphonce B, Dass Ramesh M, McHembe Mabula D, Gilyoma Japhet M

机构信息

Department of Surgery, Catholic University of Health and Allied Sciences-Bugando, Mwanza, Tanzania.

出版信息

BMC Res Notes. 2012 Jan 23;5:59. doi: 10.1186/1756-0500-5-59.

Abstract

BACKGROUND

Splenic injuries constitute a continuing diagnostic and therapeutic challenge to the trauma or general surgeons practicing in developing countries where sophisticated imaging facilities are either not available or exorbitantly expensive. The purpose of this review was to describe our own experience in the management of the splenic injuries outlining the aetiological spectrum, injury characteristics and treatment outcome of splenic injuries in our local environment and to identify predictors of outcome among these patients.

METHODS

A prospective descriptive study of splenic injury patients was carried out at Bugando Medical Centre in Northwestern Tanzania between March 2009 and February 2011. Statistical data analysis was done using SPSS software version 17.0.

RESULTS

A total of 118 patients were studied. The male to female ratio was 6.4:1. Their ages ranged from 8 to 74 years with a median age of 22 years. The modal age group was 21-30 years. The majority of patients (89.8%) had blunt trauma and road traffic accidents (63.6%) were the most frequent cause of injuries. Most patients sustained grade III (39.0%) and IV (38.1%) splenic injuries. Majority of patients (86.4%) were treated operatively with splenectomy (97.1%) being the most frequently performed procedure. Postoperative complications were recorded in 30.5% of cases. The overall length of hospital stay (LOS) ranged from 1 day to 120 days with a median of 18 days. Mortality rate was 19.5%. Patients who had severe trauma (Kampala Trauma Score II ≤ 6) and those with associated injuries stayed longer in the hospital (P < 0.001), whereas age of the patient, associated injuries, trauma scores (KTS II), grade of splenic injuries, admission systolic blood pressure ≤ 90 mmHg, estimated blood loss > 2000 mls, HIV infection with CD4 ≤ 200 cells/μl and presence of postoperative complications were significantly associated with mortality (P < 0.001).

CONCLUSION

Trauma resulting from road traffic accidents (RTAs) remains the most common cause of splenic injuries in our setting. Most of the splenic injuries were Grade III & IV and splenectomy was performed in majority of the cases. Non-operative management can be adopted in patients with blunt isolated and low grade splenic injuries but operative management is still indispensable in this part of Tanzania. Urgent preventive measures targeting at reducing the occurrence of RTAs is necessary to reduce the incidence of splenic injuries in our centre.

摘要

背景

在发展中国家,脾脏损伤对于从事创伤外科或普通外科工作的医生而言,在诊断和治疗方面一直是一项挑战,因为这些国家要么没有先进的影像设备,要么设备价格过高。本综述的目的是描述我们在脾脏损伤管理方面的经验,概述我们当地环境中脾脏损伤的病因谱、损伤特征和治疗结果,并确定这些患者预后的预测因素。

方法

2009年3月至2011年2月,在坦桑尼亚西北部的布甘多医疗中心对脾脏损伤患者进行了一项前瞻性描述性研究。使用SPSS软件17.0版进行统计数据分析。

结果

共研究了118例患者。男女比例为6.4:1。年龄范围为8至74岁,中位年龄为22岁。最常见的年龄组为21 - 30岁。大多数患者(89.8%)有钝性创伤,道路交通事故(63.6%)是最常见的损伤原因。大多数患者脾脏损伤为Ⅲ级(39.0%)和Ⅳ级(38.1%)。大多数患者(86.4%)接受了手术治疗,脾切除术(97.1%)是最常施行的手术。30.5%的病例记录有术后并发症。住院总时长从1天到120天不等,中位时长为18天。死亡率为19.5%。遭受严重创伤(坎帕拉创伤评分Ⅱ≤6)和有合并伤的患者住院时间更长(P<0.001),而患者年龄、合并伤、创伤评分(KTSⅡ)、脾脏损伤分级、入院时收缩压≤90mmHg、估计失血量>2000ml、CD4≤200细胞/μl的HIV感染以及术后并发症的存在与死亡率显著相关(P<0.001)。

结论

在我们的研究环境中,道路交通事故导致的创伤仍然是脾脏损伤最常见的原因。大多数脾脏损伤为Ⅲ级和Ⅳ级,大多数病例施行脾切除术。对于钝性孤立且低级别脾脏损伤的患者可采用非手术治疗,但在坦桑尼亚的这一地区手术治疗仍然不可或缺。为降低我们中心脾脏损伤的发生率,采取针对减少道路交通事故发生的紧急预防措施是必要的。

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