Khalifa Ahmed Aziz, Cornily Jean-Christophe, David Charles Henri, Choplain Jean-Noël, Le Gal Grégoire, Barra Jean Aubert, Bezon Eric
Department of Cardiovascular and Thoracic Surgery, Brest University Hospital, Brest, France.
Cardiology. 2011;120(4):192-9. doi: 10.1159/000335068. Epub 2012 Jan 20.
Diffuse coronary artery disease makes cardiac surgeons hesitant regarding whether coronary artery bypass grafting (CABG) surgery is feasible or not. Coronary artery reconstruction using the internal thoracic artery (ITA) allows bypassing of coronary arteries with diffuse atheromatous plaques without systematically resorting to endarterectomy. The aim of the present study was to evaluate the medium-term results of coronary artery reconstruction.
All patients undergoing coronary artery reconstruction using the ITA between 1999 and 2002 (233 patients) were included in the study. The mean age was 61.9 ± 9.8 years. Two hundred and eighty-one coronary artery reconstructions using the ITA were performed (mean length 3.6 ± 2 cm) for 514 CABGs. Coronary artery reconstruction using the ITA was associated with endarterectomy in 48 cases (17%).
In-hospital mortality was 2.6%. Follow-up data were compiled in December 2008. Mean follow-up was 73.4 ± 16.7 months. The actuarial survival rate at 7 years was 89.3 ± 2.1%, and 88% of patients were free of major cardiac events at 7 years.
Coronary artery reconstruction gives comparable medium-term results to conventional coronary surgery, even though it is indicated for patients with more severe lesions.
弥漫性冠状动脉疾病使心脏外科医生对于冠状动脉旁路移植术(CABG)是否可行犹豫不决。使用胸廓内动脉(ITA)进行冠状动脉重建可在不系统性地进行动脉内膜切除术的情况下绕过有弥漫性动脉粥样硬化斑块的冠状动脉。本研究的目的是评估冠状动脉重建的中期结果。
本研究纳入了1999年至2002年间所有接受ITA冠状动脉重建的患者(233例)。平均年龄为61.9±9.8岁。对514例CABG进行了281次ITA冠状动脉重建(平均长度3.6±2 cm)。48例(17%)ITA冠状动脉重建联合了动脉内膜切除术。
住院死亡率为2.6%。随访数据于2008年12月汇总。平均随访时间为73.4±16.7个月。7年时的精算生存率为89.3±2.1%,88%的患者在7年时无重大心脏事件。
冠状动脉重建即使适用于病变更严重的患者,其中期结果与传统冠状动脉手术相当。