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基于三嗪衍生物的杀生剂对不同基底接触的切削液微生物生物膜的影响。

Influence of a triazine derivative-based biocide on microbial biofilms of cutting fluids in contact with different substrates.

机构信息

IPEL Itibanyl Produtos Especiais Ltda., Jarinu, SP, Brazil.

出版信息

J Ind Microbiol Biotechnol. 2012 May;39(5):743-8. doi: 10.1007/s10295-011-1081-x. Epub 2012 Jan 22.

DOI:10.1007/s10295-011-1081-x
PMID:22270891
Abstract

Although biofilms are often associated with hospital infection problems owing to their high resistance to antimicrobial agents, in recent years biofilms have also been studied in the industrial sector, mainly because they are a major cause of contamination outbreaks in facilities and products. The aim of this study was to investigate whether different materials commonly found in the metalworking industries have different biofilm formation characteristics when in contact with contaminated cutting fluid as well as to establish an optimal concentration of a triazine-based antimicrobial agent to protect the oil/water emulsion and also to delay or interrupt the development of biofilms. Biofilms grown on the surface of carbon steel, stainless steel, aluminum, polyvinyl chloride, and glass were analyzed in terms of cell growth and susceptibility to the tested biocide. The results showed that the type of material used had little influence on cell adhesion or on the microbicide concentration required to control and eradicate microorganisms suspended in the emulsion and in the biofilms.

摘要

尽管生物膜因其对抗菌剂的高抵抗力而常与医院感染问题相关联,但近年来生物膜也在工业领域得到了研究,主要是因为它们是设施和产品污染爆发的主要原因。本研究的目的是研究在接触污染的切削液时,金属加工行业中常用的不同材料是否具有不同的生物膜形成特性,以及确定基于三嗪的抗菌剂的最佳浓度,以保护油/水乳液并延迟或中断生物膜的发展。对碳钢、不锈钢、铝、聚氯乙烯和玻璃表面生长的生物膜进行了细胞生长和对测试杀生物剂的敏感性分析。结果表明,所用材料的类型对细胞黏附或控制和消除乳液和生物膜中悬浮的微生物所需的微杀菌剂浓度影响不大。

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本文引用的文献

1
Prevention of bacterial adhesion.预防细菌黏附。
Appl Microbiol Biotechnol. 2010 Sep;88(2):451-9. doi: 10.1007/s00253-010-2805-y. Epub 2010 Aug 8.
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The biofilm matrix.生物膜基质。
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Biofilms, bacterial signaling, and their ties to marine biology.生物膜、细菌信号传导及其与海洋生物学的联系。
采用 MTT 法测定金属加工液中微生物的生物膜形成能力。
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The Calgary Biofilm Device: new technology for rapid determination of antibiotic susceptibilities of bacterial biofilms.卡尔加里生物膜装置:快速测定细菌生物膜抗生素敏感性的新技术。
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