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细胞内陷现象的研究进展。

Progress of research in cell-in-cell phenomena.

机构信息

Institute of Cell Biology, Zhejiang University, Hangzhou 310058, China.

出版信息

Anat Rec (Hoboken). 2012 Mar;295(3):372-7. doi: 10.1002/ar.21537. Epub 2012 Jan 23.

DOI:10.1002/ar.21537
PMID:22271432
Abstract

The discovery of a nonphagocytotic process of cell-in-cell phenomena can be traced to over a century ago. However, its biological significance remains poorly understood. Three types of cell-in-cell phenomena have been described so far, termed "cannibalism," "emperipolesis," and "entosis." These three kinds of cell-in-cell phenomena, apart from a common feature of one cell internal to another, are distinct both cytologically and biologically. In this review, we discussed them in their morphology, cell recognition, penetration mechanisms, and physiological roles, respectively.

摘要

细胞胞中现象的非吞噬性过程的发现可以追溯到一个多世纪以前。然而,其生物学意义仍未被很好地理解。迄今为止,已经描述了三种类型的细胞胞中现象,分别称为“吞噬作用”、“异噬现象”和“内吞作用”。这三种细胞胞中现象除了一个细胞内部包含另一个细胞的共同特征外,在细胞学和生物学上都有明显的区别。在这篇综述中,我们分别从形态、细胞识别、穿透机制和生理作用等方面对它们进行了讨论。

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1
Progress of research in cell-in-cell phenomena.细胞内陷现象的研究进展。
Anat Rec (Hoboken). 2012 Mar;295(3):372-7. doi: 10.1002/ar.21537. Epub 2012 Jan 23.
2
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Activated Src kinase promotes cell cannibalism in Drosophila.
激活的Src 激酶促进果蝇的细胞自噬。
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Tumor cell phagocytosis (cannibalism) in lung cancer: possible biomarker for tumor immune escape and prognosis.肺癌中的肿瘤细胞吞噬作用(自相残杀):肿瘤免疫逃逸和预后的潜在生物标志物
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CNS-localized myeloid cells capture living invading T cells during neuroinflammation.中枢神经系统局灶性髓系细胞在神经炎症期间捕获活的入侵 T 细胞。
J Exp Med. 2020 Jun 1;217(6). doi: 10.1084/jem.20190812.
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Cell-in-Cell Phenomenon and Its Relationship With Tumor Microenvironment and Tumor Progression: A Review.细胞内细胞现象及其与肿瘤微环境和肿瘤进展的关系:综述
Front Cell Dev Biol. 2019 Dec 3;7:311. doi: 10.3389/fcell.2019.00311. eCollection 2019.
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