Barbosa Carla Dias, Balp Maria-Magdalena, Kulich Károly, Germain Nicola, Rofail Diana
Mapi Consultancy, Lyon, France.
Patient Prefer Adherence. 2012;6:39-48. doi: 10.2147/PPA.S24752. Epub 2012 Jan 13.
To explore the published evidence on the link between treatment satisfaction and patients' compliance, adherence, and/or persistence.
Articles published from January 2005 to November 2010 assessing compliance, adherence, or persistence and treatment satisfaction were identified through literature searches in Medline, Embase, and PsycInfo. Abstracts were reviewed by two independent researchers who selected articles for inclusion. The main attributes of each study examining the link between satisfaction and adherence, compliance, or persistence were summarized.
The database searches yielded 1278 references. Of the 281 abstracts that met the inclusion criteria, 20 articles were retained. In the articles, adherence and compliance were often used interchangeably and various methods were used to measure these concepts. All showed a positive association between treatment satisfaction and adherence, compliance, or persistence. Sixteen studies demonstrated a statistically significant link between satisfaction and compliance or persistence. Of these, ten demonstrated a significant link between satisfaction and compliance, two showed a significant link between satisfaction and persistence, and eight demonstrated a link between either a related aspect or a component of satisfaction (eg, treatment convenience) or adherence (eg, intention to persist). An equal number of studies aimed at explaining compliance or persistence according to treatment satisfaction (n = 8) and treatment satisfaction explained by compliance or persistence (n = 8). Four studies only reported correlation coefficients, with no hypothesis about the direction of the link. The methods used to evaluate the link were varied: two studies reported the link using descriptive statistics, such as percentages, and 18 used statistical tests, such as Spearman's correlation or logistic regressions.
This review identified few studies that evaluate the statistical association between satisfaction and adherence, compliance, or persistence. The available data suggested that greater treatment satisfaction was associated with better compliance and improved persistence, and with lower regimen complexity or treatment burden.
探讨已发表的关于治疗满意度与患者依从性、持续性和/或坚持性之间联系的证据。
通过检索Medline、Embase和PsycInfo数据库，查找2005年1月至2010年11月期间发表的评估依从性、持续性或坚持性以及治疗满意度的文章。两名独立研究人员对摘要进行评审，挑选纳入的文章。总结了每项研究中关于满意度与依从性、持续性或坚持性之间联系的主要特征。
数据库检索共得到1278篇参考文献。在符合纳入标准的281篇摘要中，保留了20篇文章。在这些文章中，依从性和持续性常被互换使用，且使用了多种方法来衡量这些概念。所有研究均表明治疗满意度与依从性、持续性或坚持性之间存在正相关。16项研究表明满意度与依从性或持续性之间存在统计学显著联系。其中，10项研究表明满意度与依从性之间存在显著联系，2项研究表明满意度与持续性之间存在显著联系，8项研究表明满意度的相关方面或组成部分（如治疗便利性）与依从性（如坚持意图）之间存在联系。同样数量的研究旨在根据治疗满意度解释依从性或持续性（n = 8）以及根据依从性或持续性解释治疗满意度（n = 8）。4项研究仅报告了相关系数，未对联系方向提出假设。用于评估联系的方法各不相同：2项研究使用描述性统计（如百分比）报告联系，18项研究使用统计检验（如Spearman相关性或逻辑回归）。
本综述发现很少有研究评估满意度与依从性、持续性或坚持性之间的统计关联。现有数据表明，更高的治疗满意度与更好的依从性、更高的持续性以及更低的治疗方案复杂性或治疗负担相关。
