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农村地区创伤性横纹肌溶解症(挤压综合征)。

Traumatic rhabdomyolysis (crush syndrome) in the rural setting.

机构信息

Ngwelezane Hospital Emergency Department, Empangeni, KwaZulu-Natal.

出版信息

S Afr Med J. 2011 Dec 14;102(1):37-9.

PMID:22273136
Abstract

BACKGROUND

Patients with traumatic rhabdomyolysis (crush syndrome)(CS) secondary to community beatings commonly present to a rural emergency department that has limited access to dialysis services. We describe a retrospective study of patients admitted with a diagnosis of CS to the emergency department of a government hospital in rural KwaZulu-Natal, between November 2008 and June 2009.

OBJECTIVES

We assessed identification and management of these patients, considering: (i) early adverse parameters used to identify poor prognosis, (ii) the importance of early recognition, and (iii) appropriate management with aggressive fluid therapy and alkaline diuresis to prevent progression to renal failure.

METHODS

Diagnosis was based on clinical suspicion and haematuria. Exclusion criteria included a blood creatine kinase level <1 000 U/l on admission. Data captured included demographics, the offending weapon, time of injury and presentation to hospital, and admission laboratory results. Outcome measures included length of time in the resuscitation unit, and subsequent movement to the main ward or dialysis unit, discharge from hospital, or death.

RESULTS

Forty-four patients were included in the study (41 male, 3 female), all presenting within 24 hours of injury: 27 were assaulted with sjamboks or sticks, 43 were discharged to the ward with normal or improving renal function, and 1 patient died.

CONCLUSIONS

Serum potassium, creatinine, and creatine kinase levels were important early parameters for assessing CS severity; 43 patients (98%) had a favourable outcome, owing to early recognition and institution of appropriate therapy - vital in the absence of dialysis services.

摘要

背景

因社区殴打而导致创伤性横纹肌溶解症(挤压综合征)(CS)的患者通常会前往农村急诊部就诊,而该急诊部获取透析服务的途径有限。我们描述了一项回顾性研究,该研究纳入了 2008 年 11 月至 2009 年 6 月期间在夸祖鲁-纳塔尔省农村地区的一家政府医院急诊部就诊的 CS 诊断患者。

目的

我们评估了这些患者的识别和管理情况,考虑了以下几点:(i)用于识别不良预后的早期不良参数;(ii)早期识别的重要性;(iii)通过积极的液体疗法和碱性利尿来预防肾功能衰竭进展的适当治疗。

方法

诊断基于临床怀疑和血尿。排除标准包括入院时血肌酸激酶水平<1000U/l。收集的数据包括人口统计学资料、致伤武器、受伤时间和就诊时间,以及入院实验室结果。主要观察指标包括复苏单元的时间,随后转移到主要病房或透析单元、出院或死亡。

结果

研究纳入了 44 例患者(41 名男性,3 名女性),均在受伤后 24 小时内就诊:27 例患者被 sjamboks 或棍棒殴打,43 例患者肾功能正常或改善出院,1 例患者死亡。

结论

血清钾、肌酐和肌酸激酶水平是评估 CS 严重程度的重要早期参数;由于早期识别和适当治疗,43 例患者(98%)预后良好,这在缺乏透析服务的情况下至关重要。

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