Sellei R M, Kobbe P, Knobe M, Lichte P, Dienstknecht T, Lemmen S W, Pape H-C
Unfallchirurgische Universitätsklinik, Klinikum der RWTH Aachen, Pauwelsstr. 30, 52074 Aachen, Deutschland.
Orthopade. 2012 Jan;41(1):43-50. doi: 10.1007/s00132-011-1840-4.
Chronic osteomyelitis is a severe complication characterized by soft tissue and bone pathogenic infection resulting in osseous destruction. Surgical management is demanding and poses a challenge in achieving the goals of treatment, which are control of infection, bone healing as well as satisfactory functional outcome. Therapeutic strategies are based on a combined application of radical surgery and systemic antibiotic therapy. The bony defects which remain after extensive debridement have to be reconstructed with bone grafting after soft tissue coverage and the healing process is decisive for a successful outcome.
慢性骨髓炎是一种严重的并发症，其特征是软组织和骨发生致病性感染，导致骨质破坏。手术治疗要求高，在实现治疗目标方面面临挑战，这些目标包括控制感染、促进骨愈合以及获得满意的功能结果。治疗策略基于根治性手术和全身抗生素治疗的联合应用。广泛清创后残留的骨缺损必须在软组织覆盖后进行骨移植重建，而愈合过程对成功的治疗结果起决定性作用。
