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成人长骨骨髓炎:基本概念与当前技术

Long bone osteomyelitis in adults: fundamental concepts and current techniques.

作者信息

Sanders Julia, Mauffrey Cyril

机构信息

Department of Orthopaedics, Denver Health Medical Center, Denver, Colorado 80204, USA.

出版信息

Orthopedics. 2013 May;36(5):368-75. doi: 10.3928/01477447-20130426-07.

Abstract

Osteomyelitis is challenging for orthopedic surgeons. The fundamental basis of osteomyelitis treatment is wide surgical debridement. A variety of operative techniques exist for soft tissue coverage and segmental bony stabilization; however, extensive resection remains the crucial starting point in a comprehensive treatment plan. Antibiotic therapy continues to be a cornerstone of adjuvant therapy; nevertheless, the length of treatment is still debated. With ever-increasing antimicrobial resistance rates, targeted therapy based on accurate cultures has become imperative. Osteomyelitis requires a multidisciplinary team prepared to formulate an individualized surgical and medical plan for each patient. The aim of the current article is to highlight and summarize the current concepts in the management of long bone osteomyelitis.

摘要

骨髓炎对骨科医生来说是一项具有挑战性的疾病。骨髓炎治疗的根本基础是广泛的手术清创。软组织覆盖和节段性骨稳定存在多种手术技术;然而,广泛切除仍然是综合治疗计划的关键起点。抗生素治疗仍然是辅助治疗的基石;尽管如此,治疗时长仍存在争议。随着抗菌耐药率不断上升,基于准确培养结果的靶向治疗变得势在必行。骨髓炎需要一个多学科团队,为每位患者制定个性化的手术和医疗计划。本文的目的是突出并总结长骨骨髓炎治疗的当前概念。

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