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当地人群中迁移与DNA多态性之间的关系。

Relationship between migration and DNA polymorphism in a local population.

作者信息

Tajima F

机构信息

National Institute of Genetics, Mishima, Japan.

出版信息

Genetics. 1990 Sep;126(1):231-4. doi: 10.1093/genetics/126.1.231.

Abstract

The expected amount of DNA polymorphism, measured in terms of the number of nucleotide differences between the two DNA sequences randomly sampled from subpopulations, was studied by using the stepping-stone model and the finite island model, under the assumption that the migration rate is not the same among different subpopulations. The results obtained indicate that the expected amount of DNA polymorphism in the subpopulation with lower migration rate is smaller than that of higher migration rate. This suggests that marginal populations tend to have lower level of DNA polymorphism than central populations if the migration rate in the marginal populations is lower than that of the central populations.

摘要

在不同亚群间迁移率不同的假设下,通过使用踏脚石模型和有限岛屿模型,研究了以从亚群中随机抽取的两个DNA序列之间的核苷酸差异数量衡量的DNA多态性预期量。所得结果表明,迁移率较低的亚群中DNA多态性的预期量小于迁移率较高的亚群。这表明,如果边缘群体中的迁移率低于中心群体,那么边缘群体的DNA多态性水平往往低于中心群体。

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