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具有成骨细胞瘤样组织学特征及相关颅内气囊肿的额窦骨瘤。

Frontal sinus osteoma with osteoblastoma-like histology and associated intracranial pneumatocele.

作者信息

Lehmer Larisa M, Kissel Phillip, Ragsdale Bruce D

机构信息

Central Coast Pathology, San Luis Obispo, CA 93401, USA.

出版信息

Head Neck Pathol. 2012 Sep;6(3):384-8. doi: 10.1007/s12105-012-0332-0. Epub 2012 Jan 25.

Abstract

Osteomas of the cranial sinuses are rare, benign bony tumors that can be complicated by the formation of an intracranial pneumatocele. If not treated promptly, a pneumatocele can lead to abscess formation, meningitis, or ventriculitis. In the present case, an intracerebral pneumatocele was formed when an 18 cm(3) osteoma breached the posterior wall of the frontal sinus creating a one-way valve through which air could enter the intracranial cavity. The patient presented after forceful sneezing with nonspecific symptoms of headache, nausea, and vomiting. CT demonstrated a frontal collection of loculated air with mass effect within the left cerebral hemisphere. A partly mineralized mass occupied the left superior nasal ethmoid sinus and left frontal sinus. Of interest pathologically in this case, the tumor had a substantial osteoblastoma-like component. Surgical repair involved frontal craniotomy to remove the osteoma and debride frontal sinus mucosa, plugging the frontal nasal ducts and sinus with fat and bone wax, and dural restoration using an underwater closed drainage system to vent intracranial air and stabilize the patient.

摘要

鼻窦骨瘤是一种罕见的良性骨肿瘤,可并发颅内气囊肿形成。如果不及时治疗,气囊肿可导致脓肿形成、脑膜炎或脑室炎。在本病例中,一个18 cm³的骨瘤突破额窦后壁,形成单向瓣膜,空气可通过该瓣膜进入颅内腔,从而形成了一个脑内气囊肿。患者在用力打喷嚏后出现头痛、恶心和呕吐等非特异性症状。CT显示左脑半球有局限性积气,并伴有占位效应。一个部分矿化的肿块占据了左上颌筛窦和左额窦。在该病例中,病理检查有趣的是,肿瘤有大量成骨细胞瘤样成分。手术修复包括额部开颅术以切除骨瘤并清创额窦黏膜,用脂肪和骨蜡堵塞额鼻管和鼻窦,并使用水下闭式引流系统进行硬脑膜修复,以排出颅内空气并使患者病情稳定。

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[Benign osteoblastoma of the frontal sinus].
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