Department of Chemical, Materials, and Biomolecular Engineering, University of Connecticut, Storrs, 06269, USA.
J Biomater Appl. 2013 Feb;27(6):641-9. doi: 10.1177/0885328211419873. Epub 2012 Jan 24.
Poly(L-lactic acid) (PLLA) micro-fibers have been coated with hydroxyapatite (HA) using a quick biomimetic method to form a precursor for bone repair composites. To increase the coating content within a coating time as short as 1-2.5 h, PLLA fibers have been treated by soaking in NaOH or NaOCl solutions at mild conditions. Although different surface hydrolysis and coating methods have been used to prepare bioceramic/polymer composites, it is for the first time that the influences of the surface treatment and HA coating process on the mechanical properties of the polymer and HA/polymer composite fibers were investigated systemically.
聚（L-乳酸）（PLLA）微纤维已使用快速仿生方法涂覆羟基磷灰石（HA），以形成用于骨修复复合材料的前体。为了在尽可能短的 1-2.5 小时的涂覆时间内增加涂层含量，已经通过在温和条件下将 PLLA 纤维浸泡在 NaOH 或 NaOCl 溶液中来处理 PLLA 纤维。尽管已经使用不同的表面水解和涂层方法来制备生物陶瓷/聚合物复合材料，但这是第一次系统地研究了表面处理和 HA 涂层工艺对聚合物和 HA/聚合物复合纤维机械性能的影响。
