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PET imaging of tumor growth: not as easy as it looks.
Clin Cancer Res. 2012 Mar 1;18(5):1189-91. doi: 10.1158/1078-0432.CCR-11-3198. Epub 2012 Jan 24.
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Preliminary F-MRS Study of Tumor Cell Proliferation with 3'-deoxy-3'-fluorothymidine and Its Metabolite (FLT-MP).
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Early assessment of tumor response to JAC106, an anti-tubulin agent, by 3'-deoxy-3'-[¹⁸F]fluorothymidine in preclinical tumor models.
Eur J Nucl Med Mol Imaging. 2011 Aug;38(8):1436-48. doi: 10.1007/s00259-011-1802-4. Epub 2011 Apr 12.
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Biodistribution and uptake of 3'-deoxy-3'-fluorothymidine in ENT1-knockout mice and in an ENT1-knockdown tumor model.
J Nucl Med. 2010 Sep;51(9):1447-55. doi: 10.2967/jnumed.110.076356. Epub 2010 Aug 18.
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PET imaging of proliferation with pyrimidines.
J Nucl Med. 2013 Jun;54(6):903-12. doi: 10.2967/jnumed.112.112201. Epub 2013 May 14.
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Molecular imaging of proliferation in vivo: positron emission tomography with [18F]fluorothymidine.
Methods. 2009 Jun;48(2):205-15. doi: 10.1016/j.ymeth.2009.03.009. Epub 2009 Mar 24.

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F-FLT PET/CT as a Prognostic Imaging Biomarker of Disease-Specific Survival in Patients with Primary Soft-Tissue Sarcoma.
J Nucl Med. 2022 May;63(5):708-712. doi: 10.2967/jnumed.121.262502. Epub 2021 Sep 30.
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Glioma surveillance imaging: current strategies, shortcomings, challenges and outlook.
BJR Open. 2020 Jun 23;2(1):20200009. doi: 10.1259/bjro.20200009. eCollection 2020.
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Preclinical Applications of 3'-Deoxy-3'-[F]Fluorothymidine in Oncology - A Systematic Review.
Theranostics. 2017 Jan 1;7(1):40-50. doi: 10.7150/thno.16676. eCollection 2017.
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Metabolic Imaging to Assess Treatment Response to Cytotoxic and Cytostatic Agents.
Front Oncol. 2016 Jul 15;6:152. doi: 10.3389/fonc.2016.00152. eCollection 2016.
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¹⁸F-FLT    and ¹⁸F-FDOPA PET kinetics in recurrent brain tumors.
Eur J Nucl Med Mol Imaging. 2014 Jun;41(6):1199-209. doi: 10.1007/s00259-013-2678-2. Epub 2014 Mar 7.
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Involvement of endoplasmic reticulum stress in capsaicin-induced apoptosis of human pancreatic cancer cells.
Evid Based Complement Alternat Med. 2013;2013:629750. doi: 10.1155/2013/629750. Epub 2013 May 28.

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1
[(18)F]FLT-PET imaging does not always "light up" proliferating tumor cells.
Clin Cancer Res. 2012 Mar 1;18(5):1303-12. doi: 10.1158/1078-0432.CCR-11-1433. Epub 2011 Dec 14.
2
Early identification of antigen-specific immune responses in vivo by [18F]-labeled 3'-fluoro-3'-deoxy-thymidine ([18F]FLT) PET imaging.
Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18396-9. doi: 10.1073/pnas.1113045108. Epub 2011 Oct 24.
6
A simplified analysis of [18F]3'-deoxy-3'-fluorothymidine metabolism and retention.
Eur J Nucl Med Mol Imaging. 2005 Nov;32(11):1269-75. doi: 10.1007/s00259-005-1813-0. Epub 2005 Jul 1.

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