Karmanos Cancer Institute, Department of Oncology, Wayne State University, Detroit, Michigan 48201-2013, USA.
Clin Cancer Res. 2012 Mar 1;18(5):1189-91. doi: 10.1158/1078-0432.CCR-11-3198. Epub 2012 Jan 24.
Positron emission tomography can be used to image tumor proliferation when combined with appropriate labeled tracers, such as the thymidine analog [(18)F]-3'-deoxy-3'-fluorothymidine. Although thymidine kinase 1 is the principal mechanism of cell trapping, other variables, such as the cellular level of native thymidine, may need to be considered.
正电子发射断层扫描(Positron emission tomography)可以与适当的标记示踪剂结合使用,用于成像肿瘤增殖,例如胸苷类似物[(18)F]-3'-脱氧-3'-氟胸苷。虽然胸苷激酶 1 是细胞捕获的主要机制,但还需要考虑其他变量,例如细胞内天然胸苷的水平。