Melegari S, Albo G, Rocco B, Verweij F, Abbinante M, de Cobelli O
Department of Urology, European Institute of Oncology, Via Ripamonti 435, 20141 Milano, Italy.
Ecancermedicalscience. 2010;4:175. doi: 10.3332/ecancer.2010.175. Epub 2010 Mar 18.
adrenal gland, parotid gland, pharynx, eye and bladder are rare localizations of metastases of renal cell carcinoma (RCC). We report a case of metachronous RCC metastases to the bladder in a patient with a medical history of transitional cell carcinoma (TCC) of the bladder.
a case study and review of the relevant literature are presented.
during a follow-up cystoscopy examination following treatment of TCC, a single 5-mm lesion was detected and endoscopically resected. The histology of the resected sample was confirmed to be RCC, comparable to a primary kidney cancer and not recurrent TCC.
the patient had a probability of metastases three years after nephrectomy of 62.9%. Survival rates following single metastasectomy are 60% and 38% at three and five years, respectively; metachronous diagnosis has a better prognosis than synchronous. During RCC follow-up, each lesion should be considered as a possible metastasis of RCC.
肾上腺、腮腺、咽部、眼部和膀胱是肾细胞癌（RCC）转移的罕见部位。我们报告一例有膀胱移行细胞癌（TCC）病史的患者发生异时性RCC膀胱转移的病例。
进行病例研究并回顾相关文献。
在TCC治疗后的随访膀胱镜检查中，发现一个5毫米的单发病变并进行了内镜切除。切除样本的组织学检查证实为RCC，与原发性肾癌相符，而非复发性TCC。
该患者肾切除术后三年发生转移的概率为62.9%。单次转移灶切除术后三年和五年的生存率分别为60%和38%；异时性诊断的预后优于同时性诊断。在RCC随访期间，每个病变都应被视为RCC可能的转移灶。
