Bladder metastasis of renal cell carcinoma; a case study.

A 78-year-old man underwent left total nephroureterectomy, and histopathological examination revealed renal cell carcinoma (RCC) of clear cell subtype. Multiple lung metastases were observed, and immunotherapy using IFN-alpha was introduced after the operation. Gross hematuria was seen 1 year after the operation, and cystoscopy revealed a submucosal tumor in the bladder. Transurethral resection of the tumor was performed, and pathological diagnosis was metastasis from the RCC. Six months later, he died because of multiple metastases of the tumor. Thirty cases of metastasis of RCC to the bladder, including our case, have been reported in Japan.