神经细胞黏附分子（NCAM）与成纤维细胞生长因子受体（FGFR）信号传导之间的相互作用是卵巢癌进展的基础。
The interplay between NCAM and FGFR signalling underlies ovarian cancer progression.
作者信息
Colombo N, Cavallaro U
机构信息
Department of Gynaecological Oncology (NC), and Molecular Medicine Program (UC), European Institute of Oncology, Milano, Italy.
出版信息
Ecancermedicalscience. 2011;5:226. doi: 10.3332/ecancer.2011.226. Epub 2011 Oct 20.
Abstract
Epithelial ovarian carcinoma (EOC) is an aggressive neoplasm, which has often disseminated to peritoneal cavity at the time of diagnosis. In order to better understand the molecular mechanisms behind EOC progression, we investigated the expression and functional role of neural cell adhesion molecule (NCAM) in this tumour type.
摘要
上皮性卵巢癌（EOC）是一种侵袭性肿瘤，在诊断时往往已扩散至腹腔。为了更好地了解EOC进展背后的分子机制，我们研究了神经细胞黏附分子（NCAM）在这种肿瘤类型中的表达及功能作用。
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本文引用的文献
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2
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J Cell Biol. 2009 Dec 28;187(7):1101-16. doi: 10.1083/jcb.200903030.
3
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