Prindaville Brea, Antaya Richard J
Department of Pediatrics, Yale New Haven Hospital, New Haven, Connecticut 06510, USA.
Pediatr Dermatol. 2013 Mar-Apr;30(2):269-70. doi: 10.1111/j.1525-1470.2011.01665.x. Epub 2012 Jan 26.
Microgeodic disease, similar to chilblains (pernio), is characterized by painful, erythematous swelling, as well as small, punched-out erosions found in affected phalanges. Although they share a similar appearance and proposed pathogenesis, chilblains has rarely been diagnosed in children with microgeodic disease, and in those cases has not been confirmed on skin biopsy. This article details a child in Connecticut diagnosed during the winter with chilblains and microgeodic disease of his toe, as supported by biopsy and imaging. These findings further indicate that the two diseases are interrelated, imply a similar pathogenesis, and lead us to suggest similar treatment for problematic forms of both diseases.
微地性疾病，类似于冻疮，其特征为疼痛、红斑性肿胀，以及在受累指骨上出现的小的、穿凿状糜烂。尽管它们外观相似且发病机制推测相同，但冻疮在患有微地性疾病的儿童中很少被诊断出来，即便诊断了，皮肤活检也未得到证实。本文详细介绍了康涅狄格州一名儿童，其在冬季被诊断为脚趾冻疮和微地性疾病，活检和影像学检查均提供了支持。这些发现进一步表明这两种疾病相互关联，提示发病机制相似，并促使我们建议对这两种疾病的疑难形式采用相似的治疗方法。
