Kreth H W
Kinderklinik Universität Würzburg.
Fortschr Med. 1990 Sep 20;108(27):511-3.
Secondary immunodeficiencies are much more frequent than primary immunological disorders. There are many etiologies, such as malnutrition, cytostatic drug therapy, burns, protein-losing conditions and infections. This review briefly considers the history of virus-induced immunosuppression. Today, measles and AIDS are the most important virus-induced immunodeficiency diseases. In rate instances, infections with Epstein-Barr virus can lead to hypogammaglobulinemia and B cell lymphomas. A viral etiology should always be considered in all cases of congenital and postnatally acquired immunological disorders.
继发性免疫缺陷比原发性免疫疾病更为常见。其病因众多，如营养不良、细胞毒性药物治疗、烧伤、蛋白质丢失性疾病及感染等。本文简要回顾病毒诱导免疫抑制的历史。如今，麻疹和艾滋病是最重要的病毒诱导免疫缺陷疾病。在少数情况下，感染爱泼斯坦-巴尔病毒可导致低丙种球蛋白血症和B细胞淋巴瘤。对于所有先天性和后天获得性免疫疾病病例，均应始终考虑病毒病因。
