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[一例急性溴酸钾中毒病例]

[A case of acute potassium bromate intoxication].

作者信息

Hamada F, Ohzono S, Yamada S, Baba Y, Tokuda Y, Yamashita W, Nakashima A, Harada R, Arima T, Morita T

机构信息

Saiseikai Sendai Hospital, Kagoshima.

出版信息

Fukuoka Igaku Zasshi. 1990 Aug;81(8):271-6.

PMID:2227763
Abstract

We experienced a case of a 44 year old man who had ingested potassium bromate solution for suicide attempt. Soon after the ingestion, nausea, vomiting, abdominal pain and diarrhea developed in him. Several hours later, he began to complain of auditory disturbance and, in addition, anuric acute renal failure occurred. Direct hemoperfusion and hemodialysis was performed on the patient for the treatment purpose. Five weeks later, he was released from hemodialysis procedure. Gradually, on the other hand, progressing anemia was observed until 90th hospital day, which slowly improved thereafter. Further, pruritus, lower leg pain, headache, tinnitus and loss of sense of taste, etc. were observed in the clinical course. Renal biopsy was performed on the 119th hospital day and the specimen showed the regenerative stage of acute tubular necrosis. In our case, acute renal failure was reversible and, many other clinical manifestations were observed. However slight anemia and irreversible severe auditory disturbance remained unimproved.

摘要

我们遇到过一例44岁男性,他为自杀而摄入了溴酸钾溶液。摄入后不久,他出现恶心、呕吐、腹痛和腹泻。几小时后,他开始诉说听觉障碍,此外,还发生了无尿性急性肾衰竭。为治疗目的对该患者进行了直接血液灌流和血液透析。五周后,他停止了血液透析治疗。另一方面,逐渐观察到直至住院第90天出现进行性贫血,此后逐渐改善。此外,在临床过程中还观察到瘙痒、小腿疼痛、头痛、耳鸣和味觉丧失等症状。在住院第119天进行了肾活检,标本显示为急性肾小管坏死的再生期。在我们的病例中,急性肾衰竭是可逆的,还观察到许多其他临床表现。然而,轻度贫血和不可逆的严重听觉障碍仍未改善。

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