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老年患者心房颤动的管理与治疗

[Management and therapy of atrial fibrillation in geriatric patients].

作者信息

Gosch M, Roller R E, Böhmdorfer B, Benvenuti-Falger U, Iglseder B, Lechleitner M, Sommeregger U, Dovjak P

机构信息

Abteilung für Innere Medizin und Akutgeriatrie, Landeskrankenhaus Hochzirl, Zirl, Österreich.

出版信息

Z Gerontol Geriatr. 2012 Jan;45(1):55-66; quiz 67-8. doi: 10.1007/s00391-011-0268-0.

DOI:10.1007/s00391-011-0268-0
PMID:22278008
Abstract

Among geriatric patients, atrial fibrillation is the most common cardiac arrhythmia. In patients over 80 years of age, the prevalence rises to approximately 10%. Atrial fibrillation is associated with serious health implications, including a 2-fold increase in mortality risk and a 5-fold increase in stroke risk. In contrast to these facts, the current guidelines on the management of atrial fibrillation of the European Society of Cardiology (ESC) contain only a short paragraph on these patients. Many relevant clinical aspects go without any comment. Thus, the purpose of our paper is to discuss those special needs of geriatric patients and their physicians which are not mentioned in the guidelines of the ESC. In our review, we discuss rhythm versus rate control, oral anticoagulation, outcome, prevention, falls, adherence, polypharmacy, dementia, nursing home patients, frailty, and geriatric assessment in consideration of geriatric patients. An extended search of the literature on Pubmed served as the basis for this review. Individual aspects of each geriatric patient should be considered when managing these complex patients; however, the complexity of each case must not lead to an individualized therapy that is not in accordance with current guidelines and the literature. A large number of papers which help us to answer most of the clinical questions regarding the management of trial fibrillation in geriatric patients have already been published.

摘要

在老年患者中,心房颤动是最常见的心律失常。在80岁以上的患者中,患病率升至约10%。心房颤动与严重的健康问题相关,包括死亡风险增加两倍和中风风险增加五倍。与这些事实形成对比的是,欧洲心脏病学会(ESC)目前的心房颤动管理指南中仅用简短的一段内容提及这些患者。许多相关的临床方面未作任何评论。因此,我们本文的目的是讨论老年患者及其医生的那些在ESC指南中未提及的特殊需求。在我们的综述中,我们从老年患者的角度讨论节律控制与心率控制、口服抗凝治疗、转归、预防、跌倒、依从性、多重用药、痴呆、养老院患者、衰弱和老年评估。对PubMed上的文献进行广泛检索作为本综述的基础。在管理这些复杂患者时应考虑每位老年患者的个体情况;然而,每个病例的复杂性绝不能导致不符合当前指南和文献的个体化治疗。大量有助于我们回答有关老年患者心房颤动管理的大多数临床问题的论文已经发表。

相似文献

1
[Management and therapy of atrial fibrillation in geriatric patients].老年患者心房颤动的管理与治疗
Z Gerontol Geriatr. 2012 Jan;45(1):55-66; quiz 67-8. doi: 10.1007/s00391-011-0268-0.
2
Expert consensus of the French Society of Geriatrics and Gerontology and the French Society of Cardiology on the management of atrial fibrillation in elderly people.法国老年医学和老年学学会与法国心脏病学会关于老年人心房颤动管理的专家共识。
Arch Cardiovasc Dis. 2013 May;106(5):303-23. doi: 10.1016/j.acvd.2013.04.001. Epub 2013 May 29.
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Atrial fibrillation: state of the art.心房颤动:最新进展
Wien Klin Wochenschr. 2014 Nov;126(21-22):692-704. doi: 10.1007/s00508-014-0667-5. Epub 2014 Nov 20.
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Overview of the management of atrial fibrillation: what is the current state of the art?心房颤动的管理概述:当前的技术水平如何?
J Cardiovasc Electrophysiol. 2003 Dec;14(12 Suppl):S275-80; discussion S280. doi: 10.1046/j.1540-8167.2003.90405.x.
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Atrial fibrillation: a geriatric perspective on the 2020 ESC guidelines.心房颤动:2020 ESC 指南的老年医学视角。
Eur Geriatr Med. 2022 Feb;13(1):5-18. doi: 10.1007/s41999-021-00537-w. Epub 2021 Nov 2.
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Management of atrial fibrillation.心房颤动的管理
Herz. 2006 Dec;31(9):849-56. doi: 10.1007/s00059-006-2932-5.
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Update on the clinical management of atrial fibrillation: guidelines and beyond.心房颤动的临床管理更新:指南及其他。
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Implications for your practice: Important changes in the 2014 guideline for the management of patients with atrial fibrillation.对你临床工作的启示:2014年心房颤动患者管理指南中的重要变化。
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Atrial fibrillation.心房颤动。
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引用本文的文献

1
[Falls and dementia are not contraindications for anticoagulation in older adults with atrial fibrillation].跌倒和痴呆并非老年房颤患者抗凝治疗的禁忌证。
Z Gerontol Geriatr. 2016 Jul;49(5):458-9. doi: 10.1007/s00391-016-1088-z.
2
[Tools for optimizing pharmacotherapy for geriatric patients with multimorbidity at the end of life: helpful oder just raising awareness?].
Wien Med Wochenschr. 2014 May;164(9-10):189-94. doi: 10.1007/s10354-014-0274-0. Epub 2014 Apr 9.
3
[Digitalis and theophylline: old and superfluous?].洋地黄和茶碱:过时且多余?

本文引用的文献

1
The role of echocardiography in the management of atrial fibrillation.
Eur J Echocardiogr. 2011 Oct;12(10):i33-8. doi: 10.1093/ejechocard/jer124.
2
Rivaroxaban versus warfarin in nonvalvular atrial fibrillation.利伐沙班与华法林用于非瓣膜性心房颤动。
N Engl J Med. 2011 Sep 8;365(10):883-91. doi: 10.1056/NEJMoa1009638. Epub 2011 Aug 10.
3
Atrial fibrillation and risk of dementia: a prospective cohort study.心房颤动与痴呆风险:一项前瞻性队列研究。
J Am Geriatr Soc. 2011 Aug;59(8):1369-75. doi: 10.1111/j.1532-5415.2011.03508.x. Epub 2011 Aug 1.
Z Gerontol Geriatr. 2013 Jul;46(5):479-86; quiz 486-7. doi: 10.1007/s00391-013-0497-5.
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Outcomes and safety of antithrombotic treatment in patients aged 80 years or older with nonvalvular atrial fibrillation.80 岁及以上非瓣膜性心房颤动患者抗血栓治疗的结局和安全性。
Am J Cardiol. 2011 May 15;107(10):1489-93. doi: 10.1016/j.amjcard.2011.01.025. Epub 2011 Mar 21.
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Atrial fibrillation, anticoagulation, fall risk, and outcomes in elderly patients.老年患者心房颤动、抗凝、跌倒风险和结局。
Am Heart J. 2011 Feb;161(2):241-6. doi: 10.1016/j.ahj.2010.11.002.
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Apixaban in patients with atrial fibrillation.阿哌沙班用于房颤患者。
N Engl J Med. 2011 Mar 3;364(9):806-17. doi: 10.1056/NEJMoa1007432. Epub 2011 Feb 10.
7
Medication beliefs predict medication adherence in older adults with multiple illnesses.药物信念可预测多病老年患者的用药依从性。
J Psychosom Res. 2011 Feb;70(2):179-87. doi: 10.1016/j.jpsychores.2010.07.014. Epub 2010 Sep 18.
8
Prevalence and implications of preinjury warfarin use: an analysis of the National Trauma Databank.受伤前使用华法林的患病率及影响:对国家创伤数据库的分析
Arch Surg. 2011 May;146(5):565-70. doi: 10.1001/archsurg.2010.313. Epub 2011 Jan 17.
9
Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC).心房颤动管理指南:欧洲心脏病学会(ESC)心房颤动管理特别工作组
Eur Heart J. 2010 Oct;31(19):2369-429. doi: 10.1093/eurheartj/ehq278. Epub 2010 Aug 29.
10
Risk of intracerebral hemorrhage associated with phenprocoumon exposure: a nested case-control study in a large population-based German database.与苯丙香豆素暴露相关的脑出血风险:一项基于大型人群的德国数据库的巢式病例对照研究。
Pharmacoepidemiol Drug Saf. 2010 Jul;19(7):722-30. doi: 10.1002/pds.1973.