Chiarugi V P, Dietrich C P
J Cell Physiol. 1979 May;99(2):201-6. doi: 10.1002/jcp.1040990206.
The sulfated mucopolysaccharide composition of normal and virus transformed Balb 3T3 and BHK21 cell lines is reported. It is shown that normal 3T3 cells contain mainly chondroitin sulfate B and heparitin sulfate. Relatively higher amounts of chondroitin sulface AC were observed in polyoma virus transformed 3T3 cells, besides an absolute increase of all the three sulfated mucopolysaccharides in the polyoma and SV 40 transformed cells. It is shown also that the three sulfated mucopolysaccharides are at least in part at the cell surface. Similar differences in sulfated mucopolysaccharide composition of normal and virus transformed BHK cell lines were also observed.
报道了正常及病毒转化的Balb 3T3和BHK21细胞系的硫酸化粘多糖组成。结果表明，正常3T3细胞主要含有硫酸软骨素B和硫酸乙酰肝素。在多瘤病毒转化的3T3细胞中观察到相对较高含量的硫酸软骨素AC，此外，在多瘤病毒和SV 40转化的细胞中，所有三种硫酸化粘多糖的含量都绝对增加。还表明，这三种硫酸化粘多糖至少部分位于细胞表面。在正常和病毒转化的BHK细胞系的硫酸化粘多糖组成中也观察到了类似的差异。
