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[睡眠性头痛:13例新病例系列的特征及诊断标准修订建议]

[Hypnic headache: characteristics of a series of 13 new cases and proposal for modification of the diagnostic criteria].

作者信息

Mulero Patricia, Guerrero-Peral Angel L, Cortijo Elisa, Jabary Najaty S, Herrero-Velázquez Sonia, Miranda Sara, Penas-Martinez M Luz, Pedraza María, Fernández-Herranz Rosa

机构信息

Servicio de Neurología, Hospital Clinico Universitario de Valladolid, 47005 Valladolid, Espana.

出版信息

Rev Neurol. 2012 Feb 1;54(3):129-36.

Abstract

INTRODUCTION

Hypnic headache is a rare condition, since less than 150 cases have been reported to date. The second edition of the International Headache Classification (IHC2) has set out the diagnostic criteria of this condition, although some of them can be considered excessively strict.

AIMS

To present a series of 13 new cases of hypnic headache that were dealt with in the headache unit of a tertiary hospital and to analyse how well they fit the diagnostic criteria of the IHC2.

PATIENTS AND METHODS

Between January 2008 and January 2011, 13 patients (11 females and 2 males), out of a total of 1180 who visited the above-mentioned service (1.1%), were diagnosed with hypnic headache. The characteristics of the pain and the response to prophylactic treatment were evaluated.

RESULTS

The age of onset of the clinical signs and symptoms was 56.7 ± 9.3 years (range: 40-76 years); in two patients (15.4%) it was prior to the age of 50. The number of symptomatic nights per month was 14.5 ± 7.6 (range: 5-25); in seven cases (53.8%) the number was less than 15 nights. All the patients presented one single episode per night, with a mean duration of 53.8 ± 24.6 minutes (range: 25-120 minutes). Thirty point seven per cent of the patients did not describe their pain as dull. Sixty-one point five per cent satisfied all the IHC2 diagnostic criteria.

CONCLUSIONS

The characteristics of our series were similar to others that have recently been published. We propose that the next criteria in the IHC should include the possibility of the pain not being dull and that it occurs on fewer than 15 nights per month. The lower limit for the age of onset could be reduced to 40 years.

摘要

引言

睡眠性头痛是一种罕见病症,迄今报告的病例不足150例。《国际头痛分类》第二版(IHC2)已列出该病症的诊断标准,尽管其中一些标准可被认为过于严格。

目的

呈现一家三级医院头痛科诊治的13例新发睡眠性头痛病例系列,并分析这些病例与IHC2诊断标准的符合程度。

患者与方法

2008年1月至2011年1月期间,在上述科室就诊的1180例患者中,有13例(11例女性和2例男性,占1.1%)被诊断为睡眠性头痛。评估了疼痛特征及预防性治疗的反应。

结果

临床症状和体征的发病年龄为56.7±9.3岁(范围:40 - 76岁);2例患者(15.4%)发病年龄小于50岁。每月有症状的夜晚数为14.5±7.6(范围:5 - 25);7例患者(53.8%)该数值小于15个夜晚。所有患者每晚均发作一次,平均持续时间为53.8±24.6分钟(范围:25 - 120分钟)。30.7%的患者未将其疼痛描述为钝痛。61.5%的患者符合所有IHC2诊断标准。

结论

我们这个病例系列的特征与近期发表的其他病例系列相似。我们建议,IHC的下一版标准应纳入疼痛可能并非钝痛以及每月发作少于15个夜晚的情况。发病年龄下限可降至40岁。

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