Department of Anesthesia and Intensive Care, Helsinki Emergency Medical Services, Helsinki University Central Hospital, Helsinki, Finland.
Diabetes Care. 2012 Mar;35(3):510-2. doi: 10.2337/dc11-1478. Epub 2012 Jan 25.
To describe the trend of blood glucose immediately after successful resuscitation from out-of-hospital ventricular fibrillation.
Data from cardiac arrest registry supplemented with blood glucose data were analyzed in this population-based observational study. Between 2005 and 2009, a total of 170 adult patients survived to hospital admission after resuscitation from bystander-witnessed cardiac arrest of cardiac origin and ventricular fibrillation as an initial rhythm.
Sufficient data for analysis were available in 134 (79%) patients, of whom 87 (65% [95% CI 57-73]) survived to hospital discharge in Cerebral Performance Category 1 or 2. Blood glucose did not change significantly between prehospital (10.5 ± 4.1 mmol/L) and admission (10.0 ± 3.7 mmol/L) in survivors (P = 0.3483), whereas in nonsurvivors, blood glucose increased from 11.8 ± 4.6 to 13.8 ± 3.3 mmol/L (P = 0.0025).
Patients who are resuscitated from out-of-hospital ventricular fibrillation, but whose outcome is unfavorable are characterized by significant increase of blood glucose in the ultraacute postresuscitation phase.
描述院外室颤心肺复苏成功后即刻血糖的变化趋势。
本研究为基于人群的观察性研究，对来自心脏骤停登记处的数据进行了补充血糖数据的分析。在 2005 年至 2009 年期间，共有 170 名经旁观者目击的起源于心源性和室颤的心脏骤停复苏后存活至入院的成年患者。
在可进行分析的 134 名患者（79%）中，有 87 名（65%[95%CI57-73%]）患者存活至出院时的脑功能状态分类 1 或 2 级。幸存者的血糖在院前（10.5±4.1mmol/L）和入院时（10.0±3.7mmol/L）之间没有明显变化（P=0.3483），而在非幸存者中，血糖从 11.8±4.6mmol/L 增加到 13.8±3.3mmol/L（P=0.0025）。
从院外室颤中复苏但预后不良的患者，在超急性复苏后阶段血糖显著升高。
