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使用亚洲流行模型评估避孕套使用和标准化性传播疾病治疗对湖南省男男性行为者预防艾滋病毒的影响

Impact of condom use and standardized sexually transmitted disease treatment on HIV prevention among men who have sex with men in hunan province: using the Asian epidemic model.

作者信息

Ma Ning, Zheng Min, Liu Min, Chen Xi, Zheng Jun, Chen Hong-guang, Wang Ning

机构信息

Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.

出版信息

AIDS Res Hum Retroviruses. 2012 Oct;28(10):1273-9. doi: 10.1089/AID.2011.0294. Epub 2012 Mar 27.

Abstract

We evaluated the HIV/AIDS epidemic among men who have sex with men (MSM) in Hunan Province using the Asian Epidemic Model (AEM) and explored the impact of both condom use and standardized STD treatment on HIV prevention programs. The AEM was used to estimate HIV infection under four different scenarios: (1) condom use among MSM maintained at the 2005 level, (2) condom use among MSM improved since 2005, (3) the sexually transmitted infection (STI) prevalence rate among MSM maintained at the 2008 level, and (4) the STI prevalence rate among MSM improved since 2008. Compared with the rate of condom use at the 2005 level among MSM, if the rate of condom use had continuously improved, the number of new infections would have been reduced by 79.1% and the number of people living with HIV and AIDS would decrease by more than 8600 by 2020 and the cumulative number of new infections would have been reduced by 63.6% since 2006 while the number of new HIV infections among females would decline from 2015 with a drop of over 35% by 2020. When compared with the projection based on an unchanged rate of STI infection, the number of new HIV infections would decrease by 49.4% by 2020, and the decreased number of people living with HIV and AIDS would be more than 4000. The total number of 5200 newly infected HIV cases could be reduced from 2006 to 2020 and the number of newly infected HIV cases among the general female population would be reduced by 15.4%. With both the increased rate of condom use and standardized STD treatment for the MSM population in Hunan Province, the spread of HIV infection in both MSM and the general female population would decrease.

摘要

我们使用亚洲流行模型(AEM)评估了湖南省男男性行为者(MSM)中的艾滋病毒/艾滋病疫情,并探讨了使用避孕套和标准化性传播疾病治疗对艾滋病毒预防计划的影响。AEM用于估计四种不同情况下的艾滋病毒感染情况:(1)男男性行为者中的避孕套使用率维持在2005年的水平;(2)自2005年以来男男性行为者中的避孕套使用率有所提高;(3)男男性行为者中的性传播感染(STI)患病率维持在2008年的水平;(4)自2008年以来男男性行为者中的性传播感染患病率有所提高。与男男性行为者2005年水平的避孕套使用率相比,如果避孕套使用率持续提高,到2020年新感染人数将减少79.1%,艾滋病毒/艾滋病感染者人数将减少8600多人,自2006年以来新感染累计人数将减少63.6%,而女性中新感染艾滋病毒的人数将从2015年开始下降,到2020年下降超过35%。与基于性传播感染率不变的预测相比,到2020年新感染艾滋病毒的人数将减少49.4%,艾滋病毒/艾滋病感染者减少的人数将超过4000人。2006年至2020年期间,新增艾滋病毒感染病例总数可减少5200例,普通女性人群中新感染艾滋病毒病例数将减少15.4%。随着湖南省男男性行为者人群避孕套使用率的提高和性传播疾病的标准化治疗,男男性行为者和普通女性人群中艾滋病毒感染的传播都将减少。

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