Beijing Chaoyang District Centre for Disease Control and Prevention, No. 25 Panjiayuan Huaweili, Chaoyang District, Beijing, China.
Peking University, School of Public Health, No. 38 Xueyuan Road, Haidian District, Beijing, China.
BMC Infect Dis. 2018 Mar 13;18(1):124. doi: 10.1186/s12879-018-3026-8.
Condom use and antiretroviral therapy (ART) are effective means to prevent and control HIV transmission. We aimed to assess the effect of condom use in combination with antiretroviral therapy (ART) on HIV incidence and mortality among men who had sex with men (MSM) in Beijing, China.
We evaluated the effect of condom use, ART, and the combination of both among people living with HIV/AIDS (PLWHA) of MSM in the Chaoyang District of Beijing using the Asian Epidemic Model (AEM). Evaluation indicators included absolute risk reduction (ARR) and the percentage of relative risk reduction (RRR %).
HIV incidence and prevalence declined substantially when condoms were used by MSM in Chaoyang from 2003 to 2013. The ARR of HIV incidence was from 0 to 0.91% and the RRR% was from 0 to 43.93%. The ARR of HIV prevalence was from 0 to 3.79% and the RRR% was from 0 to 31.53%. The HIV mortality rate decreased substantially (ARR from 0 to 1.75%, and RRR% from 0 to 40.03%) when ART was implemented. When condom use combined with ART was implemented in MSM in 2003-2013, HIV incidence declined substantially (ARR from 0 to 0.99%, and RRR% from 0 to 46.11%). HIV prevalence was also reduced with an ARR from 0 to 3.5%, and an RRR% from 0 to 29.88%. The HIV mortality also declined substantially (ARR from - 0.01% to 1.02%, RRR% from - 1.44% to 39.98%).
Among MSM, a combination of condom use and ART reduces both HIV incidence and mortality caused by HIV. Combining these methods results in a more effective prevention and control of HIV.
安全套的使用和抗逆转录病毒疗法（ART）是预防和控制 HIV 传播的有效手段。我们旨在评估安全套的使用与抗病毒治疗（ART）相结合对中国北京男男性行为者（MSM）中 HIV 发病率和死亡率的影响。
我们使用亚洲流行模型（AEM）评估了北京朝阳区 HIV/AIDS（PLWHA）人群中安全套使用、ART 以及两者结合对 MSM 的影响。评估指标包括绝对风险降低（ARR）和相对风险降低（RRR）的百分比。
从 2003 年到 2013 年，朝阳 MSM 使用安全套后，HIV 发病率和流行率显著下降。HIV 发病率的 ARR 从 0 到 0.91%，RRR%从 0 到 43.93%。HIV 患病率的 ARR 从 0 到 3.79%，RRR%从 0 到 31.53%。实施 ART 后，HIV 死亡率显著下降（ARR 从 0 到 1.75%，RRR%从 0 到 40.03%）。2003-2013 年，当 MSM 中同时使用安全套和 ART 时，HIV 发病率显著下降（ARR 从 0 到 0.99%，RRR%从 0 到 46.11%）。HIV 患病率也有所下降，ARR 从 0 到 3.5%，RRR%从 0 到 29.88%。HIV 死亡率也显著下降（ARR 从-0.01%到 1.02%，RRR%从-1.44%到 39.98%）。
在 MSM 中，安全套的使用和 ART 的结合降低了 HIV 引起的 HIV 发病率和死亡率。将这些方法结合起来，可以更有效地预防和控制 HIV。
