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益生菌作为预防和治疗人类疾病的替代策略:综述

Probiotics as an alternative strategy for prevention and treatment of human diseases: a review.

作者信息

Khani Soghra, Hosseini Hamideh M, Taheri Mohammad, Nourani Mohammad R, Imani Fooladi Abbas A

机构信息

Department of Biochemistry, Pasteur Institute of Iran, Tehran, Iran.

出版信息

Inflamm Allergy Drug Targets. 2012 Apr;11(2):79-89. doi: 10.2174/187152812800392832.

Abstract

Probiotics are live microbial food supplements or their components, which have been shown to have beneficial effects on human health. Probiotics can be bacteria, molds, or yeasts, but most of them fall into the group known as lactic acid bacteria and are normally consumed in the form of yogurt, fermented milk, or other fermented foods. Data from clinical trials have shown contrasting effects and should be interpreted with caution. A large variety of potential beneficial effects have been reported including improvement of intestinal tract health, enhancing the immune system, reducing symptoms of lactose intolerance, decreasing the prevalence of allergy in susceptible individuals, reducing risk of certain cancers, treating colitis, lowering serum cholesterol concentrations, reducing blood pressure in hypertensives, and improving female urogenital infections and Helicobacter pylori infections. The aim of this article is to present a review of the current expanding knowledge of applications of utilizing probiotic microorganisms in the prevention and treatment of several diseases.

摘要

益生菌是活的微生物食品补充剂或其成分,已被证明对人体健康有益。益生菌可以是细菌、霉菌或酵母,但大多数属于乳酸菌类别,通常以酸奶、发酵乳或其他发酵食品的形式食用。临床试验数据显示出不同的效果,应谨慎解读。据报道,益生菌有多种潜在的有益作用,包括改善肠道健康、增强免疫系统、减轻乳糖不耐受症状、降低易感个体的过敏发生率、降低某些癌症的风险、治疗结肠炎、降低血清胆固醇浓度、降低高血压患者的血压,以及改善女性泌尿生殖系统感染和幽门螺杆菌感染。本文旨在综述目前关于利用益生菌微生物预防和治疗多种疾病的应用方面不断扩展的知识。

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