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益生菌对乳糖不耐受的影响:系统评价。

The effects of probiotics in lactose intolerance: A systematic review.

机构信息

a Department of Human Nutrition , Food and Animal Sciences, College of Tropical Agriculture and Human Resources, University of Hawaii at Manoa , Honolulu , HI , USA.

出版信息

Crit Rev Food Sci Nutr. 2019;59(11):1675-1683. doi: 10.1080/10408398.2018.1425977. Epub 2018 Feb 9.

DOI:10.1080/10408398.2018.1425977
PMID:29425071
Abstract

Over 60 percent of the human population has a reduced ability to digest lactose due to low levels of lactase enzyme activity. Probiotics are live bacteria or yeast that supplements the gastrointestinal flora. Studies have shown that probiotics exhibit various health beneficial properties such as improvement of intestinal health, enhancement of the immune responses, and reduction of serum cholesterol. Accumulating evidence has shown that probiotic bacteria in fermented and unfermented milk products can be used to alleviate the clinical symptoms of lactose intolerance (LI). In this systematic review, the effectiveness of probiotics in the treatment of LI was evaluated using 15 randomized double-blind studies. Eight probiotic strains with the greatest number of proven benefits were studied. Results showed varying degrees of efficacy but an overall positive relationship between probiotics and lactose intolerance.

摘要

由于乳糖酶活性水平低,超过 60%的人类人群消化乳糖的能力降低。益生菌是一种活菌或酵母,可以补充胃肠道菌群。研究表明,益生菌具有多种有益健康的特性,如改善肠道健康、增强免疫反应和降低血清胆固醇。越来越多的证据表明,发酵和未发酵的奶制品中的益生菌可用于缓解乳糖不耐受(LI)的临床症状。在这项系统评价中,使用了 15 项随机双盲研究来评估益生菌治疗 LI 的效果。研究了 8 种具有最多已证明益处的益生菌菌株。结果显示出不同程度的疗效,但益生菌与乳糖不耐受之间存在总体的积极关系。

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