Department of Biochemistry, Ankara University Veterinary Medicine Faculty, Ankara, Turkey.
Int J Radiat Biol. 2012 May;88(5):414-9. doi: 10.3109/09553002.2012.661517. Epub 2012 Mar 2.
Environmental electromagnetic fields originate from man-made sources, such as mobile phones and base stations, and have led to increasing public concern about their possible adverse health effects. We aimed to investigate the possible effects of radiofrequency radiation (RFR) generated from these devices on oversensitive animals, such as pregnant rabbits.
In the present study, the effects of whole body 1800 MHz Global System for Mobile Communications (GSM)-like RFR exposure for 15 min/day for seven days on blood chemistry and lipid peroxidation levels in both non-pregnant and pregnant New Zealand White rabbits were investigated. Thirteen-month-old rabbits were studied in the following four groups: Non-pregnant control, non-pregnant RFR-exposed, pregnant control and pregnant RFR-exposed.
Lipid peroxidation, namely malondialdehyde (MDA) levels, did not change after RFR exposure. However, blood chemistry parameters, such as cholesterol (CHO), total protein (TP), albumin (ALB), uric acid, creatinin and creatine kinase (CK) and creatine kinase-myocardial band isoenzyme (CK-MB) changed due to both pregnancy and RFR exposure.
Our investigations have been shown that no indication for oxidative stress was detected in the blood of pregnant rabbits upon RF exposure at specific conditions employed in the present study. Minor changes in some blood chemistry parameters were detected but CK-MB and CK increases were found remarkable. Studies on RFR exposure during pregnancy will help establish international standards for the protection of pregnant women from environmental RFR.
环境电磁场源于人为来源，如移动电话和基站，并导致公众对其可能产生的不良健康影响的担忧日益增加。我们旨在研究这些设备产生的射频辐射（RFR）对过度敏感的动物（如怀孕的兔子）可能产生的影响。
在本研究中，研究了全身 1800 MHz 全球移动通信系统（GSM）样 RFR 暴露 15 分钟/天，持续 7 天对非怀孕和怀孕新西兰白兔的血液化学和脂质过氧化水平的影响。研究了 13 个月大的兔子，分为以下四组：非怀孕对照组、非怀孕 RFR 暴露组、怀孕对照组和怀孕 RFR 暴露组。
RFR 暴露后脂质过氧化，即丙二醛（MDA）水平没有变化。然而，由于怀孕和 RFR 暴露，血液化学参数，如胆固醇（CHO）、总蛋白（TP）、白蛋白（ALB）、尿酸、肌酐和肌酸激酶（CK）以及肌酸激酶-心肌带同工酶（CK-MB）发生了变化。
我们的研究表明，在本研究中采用的特定条件下，RF 暴露并未在怀孕兔子的血液中检测到氧化应激的迹象。尽管检测到一些血液化学参数的微小变化，但 CK-MB 和 CK 的增加是显著的。对怀孕期间 RFR 暴露的研究将有助于为保护孕妇免受环境 RFR 建立国际标准。
